Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation.
Evankovich J, Lear T, Mckelvey A, Dunn S, Londino J, Liu Y, Chen BB, Mallampalli RK.
Evankovich J, et al. Among authors: lear t.
FASEB J. 2017 Sep;31(9):3894-3903. doi: 10.1096/fj.201700031R. Epub 2017 May 17.
FASEB J. 2017.
PMID: 28515150
Free PMC article.
Here we show that RAGE exhibits an extended life span in lung epithelia (t() 6 h), is monoubiquitinated at K374, and is degraded in lysosomes. The RAGE ligand ODN2006, a synthetic oligodeoxynucleotide resembling pathogenic hypomethylated CpG DNA, promotes rapid lysosomal R …
Here we show that RAGE exhibits an extended life span in lung epithelia (t() 6 h), is monoubiquitinated at K374, and is degraded in l …