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BIRC6 mediates imatinib resistance independently of Mcl-1.
Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. Okumu DO, et al. Among authors: zhang r, zhang y. PLoS One. 2017 May 16;12(5):e0177871. doi: 10.1371/journal.pone.0177871. eCollection 2017. PLoS One. 2017. PMID: 28520795 Free PMC article.
Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.
Liu Y, He Y, Jin A, Tikunov AP, Zhou L, Tollini LA, Leslie P, Kim TH, Li LO, Coleman RA, Gu Z, Chen YQ, Macdonald JM, Graves LM, Zhang Y. Liu Y, et al. Among authors: zhang y. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2414-22. doi: 10.1073/pnas.1315605111. Epub 2014 May 28. Proc Natl Acad Sci U S A. 2014. PMID: 24872453 Free PMC article.
p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression.
Liu Y, Leslie PL, Jin A, Itahana K, Graves LM, Zhang Y. Liu Y, et al. Among authors: zhang y. FASEB J. 2018 Jul;32(7):3892-3902. doi: 10.1096/fj.201701004RR. Epub 2018 Feb 20. FASEB J. 2018. PMID: 29465311 Free PMC article.
Thus, p32 and GCS1 are regulators of ER function and lipid homeostasis and are potential therapeutic targets for the treatment of obesity and diabetes.-Liu, Y., Leslie, P. L., Jin, A., Itahana, K., Graves, L. M., Zhang, Y. p32 regulates ER stress and lipid ho …
Thus, p32 and GCS1 are regulators of ER function and lipid homeostasis and are potential therapeutic targets for the treatment of obesity an …
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