Hou L - Search Results

1

Molecular assembly of rhodopsin with G protein-coupled receptor kinases.

He Y, Gao X, Goswami D, Hou L, Pal K, Yin Y, Zhao G, Ernst OP, Griffin P, Melcher K, Xu HE. He Y, et al. Among authors: hou l. Cell Res. 2017 Jun;27(6):728-747. doi: 10.1038/cr.2017.72. Epub 2017 May 19. Cell Res. 2017. PMID: 28524165 Free PMC article.

2

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.

Zhao LH, Zhou XE, Wu ZS, Yi W, Xu Y, Li S, Xu TH, Liu Y, Chen RZ, Kovach A, Kang Y, Hou L, He Y, Xie C, Song W, Zhong D, Xu Y, Wang Y, Li J, Zhang C, Melcher K, Xu HE. Zhao LH, et al. Among authors: hou l. Cell Res. 2013 Mar;23(3):436-9. doi: 10.1038/cr.2013.19. Epub 2013 Feb 5. Cell Res. 2013. PMID: 23381136 Free PMC article. No abstract available.

3

Structures and mechanism for the design of highly potent glucocorticoids.

He Y, Yi W, Suino-Powell K, Zhou XE, Tolbert WD, Tang X, Yang J, Yang H, Shi J, Hou L, Jiang H, Melcher K, Xu HE. He Y, et al. Among authors: hou l. Cell Res. 2014 Jun;24(6):713-26. doi: 10.1038/cr.2014.52. Epub 2014 Apr 25. Cell Res. 2014. PMID: 24763108 Free PMC article.

4

Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.

Zhao LH, Zhou XE, Yi W, Wu Z, Liu Y, Kang Y, Hou L, de Waal PW, Li S, Jiang Y, Scaffidi A, Flematti GR, Smith SM, Lam VQ, Griffin PR, Wang Y, Li J, Melcher K, Xu HE. Zhao LH, et al. Among authors: hou l. Cell Res. 2015 Nov;25(11):1219-36. doi: 10.1038/cr.2015.122. Epub 2015 Oct 16. Cell Res. 2015. PMID: 26470846 Free PMC article.

5

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.

Zhao LH, Yin Y, Yang D, Liu B, Hou L, Wang X, Pal K, Jiang Y, Feng Y, Cai X, Dai A, Liu M, Wang MW, Melcher K, Xu HE. Zhao LH, et al. Among authors: hou l. J Biol Chem. 2016 Jul 15;291(29):15119-30. doi: 10.1074/jbc.M116.726620. Epub 2016 May 13. J Biol Chem. 2016. PMID: 27226600 Free PMC article.

6

The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer.

Liu P, Jia MZ, Zhou XE, De Waal PW, Dickson BM, Liu B, Hou L, Yin YT, Kang YY, Shi Y, Melcher K, Xu HE, Jiang Y. Liu P, et al. Among authors: hou l. Acta Pharmacol Sin. 2016 Sep;37(9):1259-72. doi: 10.1038/aps.2016.69. Epub 2016 Aug 8. Acta Pharmacol Sin. 2016. PMID: 27498775 Free PMC article.

7

An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain.

Yin Y, Zhou XE, Hou L, Zhao LH, Liu B, Wang G, Jiang Y, Melcher K, Xu HE. Yin Y, et al. Among authors: hou l. Cell Discov. 2016 Nov 22;2:16042. doi: 10.1038/celldisc.2016.42. eCollection 2016. Cell Discov. 2016. PMID: 27917297 Free PMC article.

8

Ligand-induced activation of ERK1/2 signaling by constitutively active G_s-coupled 5-HT receptors.

Liu P, Yin YL, Wang T, Hou L, Wang XX, Wang M, Zhao GG, Shi Y, Xu HE, Jiang Y. Liu P, et al. Among authors: hou l. Acta Pharmacol Sin. 2019 Sep;40(9):1157-1167. doi: 10.1038/s41401-018-0204-6. Epub 2019 Mar 4. Acta Pharmacol Sin. 2019. PMID: 30833707 Free PMC article.

9

Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3.

Shao Z, Tan Y, Shen Q, Hou L, Yao B, Qin J, Xu P, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, Chen ZH, Jiang Y, Xu HE, Ying S, Ma H, Zhang Y, Shen H. Shao Z, et al. Among authors: hou l. Cell Discov. 2022 May 15;8(1):44. doi: 10.1038/s41421-022-00403-4. Cell Discov. 2022. PMID: 35570218 Free PMC article.

10

Structural insight into GPR55 ligand recognition and G-protein coupling.

Xia R, Yuan Q, Wang N, Hou L, Abe J, Song J, Ito Y, Xu HE, He Y. Xia R, et al. Among authors: hou l. Cell Res. 2025 Jan;35(1):76-79. doi: 10.1038/s41422-024-01044-w. Epub 2024 Oct 31. Cell Res. 2025. PMID: 39482404 Free PMC article. No abstract available.

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