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Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases.
McNally JP, Millen SH, Chaturvedi V, Lakes N, Terrell CE, Elfers EE, Carroll KR, Hogan SP, Andreassen PR, Kanter J, Allen CE, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Joyce M, Hildeman DA, Katz JD, Jordan MB. McNally JP, et al. Among authors: jordan mb. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4782-E4791. doi: 10.1073/pnas.1703683114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533414 Free PMC article.
Mice with a selective impairment of IFN-gamma signaling in macrophage lineage cells demonstrate the critical role of IFN-gamma-activated macrophages for the control of protozoan parasitic infections in vivo.
Lykens JE, Terrell CE, Zoller EE, Divanovic S, Trompette A, Karp CL, Aliberti J, Flick MJ, Jordan MB. Lykens JE, et al. Among authors: jordan mb. J Immunol. 2010 Jan 15;184(2):877-85. doi: 10.4049/jimmunol.0902346. Epub 2009 Dec 14. J Immunol. 2010. PMID: 20018611 Free PMC article.
Perforin is a critical physiologic regulator of T-cell activation.
Lykens JE, Terrell CE, Zoller EE, Risma K, Jordan MB. Lykens JE, et al. Among authors: jordan mb. Blood. 2011 Jul 21;118(3):618-26. doi: 10.1182/blood-2010-12-324533. Epub 2011 May 23. Blood. 2011. PMID: 21606480 Free PMC article.
Hemophagocytosis causes a consumptive anemia of inflammation.
Zoller EE, Lykens JE, Terrell CE, Aliberti J, Filipovich AH, Henson PM, Jordan MB. Zoller EE, et al. Among authors: jordan mb. J Exp Med. 2011 Jun 6;208(6):1203-14. doi: 10.1084/jem.20102538. Epub 2011 May 30. J Exp Med. 2011. PMID: 21624938 Free PMC article.
How I treat hemophagocytic lymphohistiocytosis.
Jordan MB, Allen CE, Weitzman S, Filipovich AH, McClain KL. Jordan MB, et al. Blood. 2011 Oct 13;118(15):4041-52. doi: 10.1182/blood-2011-03-278127. Epub 2011 Aug 9. Blood. 2011. PMID: 21828139 Free PMC article. Review.
Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab.
Marsh RA, Allen CE, McClain KL, Weinstein JL, Kanter J, Skiles J, Lee ND, Khan SP, Lawrence J, Mo JQ, Bleesing JJ, Filipovich AH, Jordan MB. Marsh RA, et al. Among authors: jordan mb. Pediatr Blood Cancer. 2013 Jan;60(1):101-9. doi: 10.1002/pbc.24188. Epub 2012 Apr 22. Pediatr Blood Cancer. 2013. PMID: 22522603 Free PMC article.
149 results