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Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.
Skarbek C, Lesueur LL, Chapuis H, Deroussent A, Pioche Durieu C, Daville A, Caron J, Rivard M, Martens T, Bertrand JR, Le Cam E, Vassal G, Couvreur P, Desmaele D, Paci A. Skarbek C, et al. Among authors: couvreur p. J Med Chem. 2015 Jan 22;58(2):705-17. doi: 10.1021/jm501224x. Epub 2014 Dec 23. J Med Chem. 2015. PMID: 25494842
Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study.
Deroussent A, Skarbek C, Maury A, Chapuis H, Daudigeos-Dubus E, Le Dret L, Durand S, Couvreur P, Desmaële D, Paci A. Deroussent A, et al. Among authors: couvreur p. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jun 15;992:30-5. doi: 10.1016/j.jchromb.2015.04.025. Epub 2015 Apr 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25939095
A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary.
Skanji R, Andrieux K, Lalanne M, Caron J, Bourgaux C, Degrouard J, Brisset F, Gueutin C, Chacun H, Dereuddre-Bosquet N, Paci A, Vassal G, Bauduin L, Garcia-Argote S, Rousseau B, Clayette P, Desmaële D, Couvreur P. Skanji R, et al. Among authors: couvreur p. Int J Pharm. 2011 Jul 29;414(1-2):285-97. doi: 10.1016/j.ijpharm.2011.05.005. Epub 2011 May 10. Int J Pharm. 2011. PMID: 21596125
X-ray microfluorescence for biodistribution studies of nanomedicines.
Epaule C, Maksimenko A, Bastian G, Caron J, Desmaële D, Zouhiri F, Couvreur P, Doucet J. Epaule C, et al. Among authors: couvreur p. Int J Pharm. 2017 Oct 5;531(1):343-349. doi: 10.1016/j.ijpharm.2017.08.106. Epub 2017 Aug 26. Int J Pharm. 2017. PMID: 28851573
470 results