Wu X - Search Results

1

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.

Yin JC, Platt MJ, Tian X, Wu X, Backx PH, Simpson JA, Araki T, Neel BG. Yin JC, et al. Among authors: wu x. Nat Commun. 2017 May 26;8:15518. doi: 10.1038/ncomms15518. Nat Commun. 2017. PMID: 28548091 Free PMC article.

2

MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation.

Wu X, Simpson J, Hong JH, Kim KH, Thavarajah NK, Backx PH, Neel BG, Araki T. Wu X, et al. J Clin Invest. 2011 Mar;121(3):1009-25. doi: 10.1172/JCI44929. Epub 2011 Feb 21. J Clin Invest. 2011. PMID: 21339642 Free PMC article.

3

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.

Marin TM, Keith K, Davies B, Conner DA, Guha P, Kalaitzidis D, Wu X, Lauriol J, Wang B, Bauer M, Bronson R, Franchini KG, Neel BG, Kontaridis MI. Marin TM, et al. Among authors: wu x. J Clin Invest. 2011 Mar;121(3):1026-43. doi: 10.1172/JCI44972. Epub 2011 Feb 21. J Clin Invest. 2011. PMID: 21339643 Free PMC article.

4

Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants.

Wu X, Yin J, Simpson J, Kim KH, Gu S, Hong JH, Bayliss P, Backx PH, Neel BG, Araki T. Wu X, et al. Mol Cell Biol. 2012 Oct;32(19):3872-90. doi: 10.1128/MCB.00751-12. Epub 2012 Jul 23. Mol Cell Biol. 2012. PMID: 22826437 Free PMC article.

5

Lung Adenocarcinoma Harboring EGFR 19del/C797S/T790M Triple Mutations Responds to Brigatinib and Anti-EGFR Antibody Combination Therapy.

Wang X, Zhou L, Yin JC, Wu X, Shao YW, Gao B. Wang X, et al. Among authors: wu x. J Thorac Oncol. 2019 May;14(5):e85-e88. doi: 10.1016/j.jtho.2019.01.015. Epub 2019 Jan 31. J Thorac Oncol. 2019. PMID: 30711650 Free article. No abstract available.

6

Comprehensive Genomic Profiling Identifies Novel Genetic Predictors of Response to Anti-PD-(L)1 Therapies in Non-Small Cell Lung Cancer.

Fang W, Ma Y, Yin JC, Hong S, Zhou H, Wang A, Wang F, Bao H, Wu X, Yang Y, Huang Y, Zhao H, Shao YW, Zhang L. Fang W, et al. Among authors: wu x. Clin Cancer Res. 2019 Aug 15;25(16):5015-5026. doi: 10.1158/1078-0432.CCR-19-0585. Epub 2019 May 13. Clin Cancer Res. 2019. PMID: 31085721

7

Developing more sensitive genomic approaches to detect radioresponse in precision radiation oncology: From tissue DNA analysis to circulating tumor DNA.

He K, Zhang S, Shao LL, Yin JC, Wu X, Shao YW, Yuan S, Yu J. He K, et al. Among authors: wu x. Cancer Lett. 2020 Mar 1;472:108-118. doi: 10.1016/j.canlet.2019.12.004. Epub 2019 Dec 16. Cancer Lett. 2020. PMID: 31837443

8

Combinatorial assessment of ctDNA release and mutational burden predicts anti-PD(L)1 therapy outcome in nonsmall-cell lung cancer.

Fang W, Ma Y, Yin JC, Zhou H, Wang F, Bao H, Wang A, Wu X, Hong S, Yang Y, Huang Y, Zhao H, Shao YW, Zhang L. Fang W, et al. Among authors: wu x. Clin Transl Med. 2020 Jan;10(1):331-336. doi: 10.1002/ctm2.8. Clin Transl Med. 2020. PMID: 32508057 Free PMC article. No abstract available.

9

Rare mutation-dominant compound EGFR-positive NSCLC is associated with enriched kinase domain-resided variants of uncertain significance and poor clinical outcomes.

Zhao W, Song A, Xu Y, Wu Q, Liu C, Yin JC, Ou Q, Wu X, Shao Y, Zhao X. Zhao W, et al. Among authors: wu x, wu q. BMC Med. 2023 Feb 24;21(1):73. doi: 10.1186/s12916-023-02768-z. BMC Med. 2023. PMID: 36829178 Free PMC article.

10

Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Li Z, Huang W, Yin JC, Na C, Wu X, Shao Y, Ding H, Li J. Li Z, et al. Among authors: wu x. Clin Transl Med. 2020 Nov;10(7):e222. doi: 10.1002/ctm2.222. Clin Transl Med. 2020. PMID: 33252848 Free PMC article. No abstract available.

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