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The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.
Loiseau L, Fyfe C, Aussel L, Hajj Chehade M, Hernández SB, Faivre B, Hamdane D, Mellot-Draznieks C, Rascalou B, Pelosi L, Velours C, Cornu D, Lombard M, Casadesús J, Pierrel F, Fontecave M, Barras F. Loiseau L, et al. Among authors: fyfe c. J Biol Chem. 2017 Jul 14;292(28):11937-11950. doi: 10.1074/jbc.M117.789164. Epub 2017 May 30. J Biol Chem. 2017. PMID: 28559279 Free PMC article.
A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Hajj Chehade M, Pelosi L, Fyfe CD, Loiseau L, Rascalou B, Brugière S, Kazemzadeh K, Vo CD, Ciccone L, Aussel L, Couté Y, Fontecave M, Barras F, Lombard M, Pierrel F. Hajj Chehade M, et al. Cell Chem Biol. 2019 Apr 18;26(4):482-492.e7. doi: 10.1016/j.chembiol.2018.12.001. Epub 2019 Jan 24. Cell Chem Biol. 2019. PMID: 30686758 Free article.
Making the invisible enemy visible.
Croll TI, Diederichs K, Fischer F, Fyfe CD, Gao Y, Horrell S, Joseph AP, Kandler L, Kippes O, Kirsten F, Müller K, Nolte K, Payne AM, Reeves M, Richardson JS, Santoni G, Stäb S, Tronrud DE, von Soosten LC, Williams CJ, Thorn A. Croll TI, et al. Among authors: fyfe cd. Nat Struct Mol Biol. 2021 May;28(5):404-408. doi: 10.1038/s41594-021-00593-7. Nat Struct Mol Biol. 2021. PMID: 33972785 Free PMC article.
Making the invisible enemy visible.
Croll T, Diederichs K, Fischer F, Fyfe C, Gao Y, Horrell S, Joseph AP, Kandler L, Kippes O, Kirsten F, Müller K, Nolte K, Payne A, Reeves MG, Richardson J, Santoni G, Stäb S, Tronrud D, von Soosten L, Williams C, Thorn A. Croll T, et al. Among authors: fyfe c. bioRxiv [Preprint]. 2020 Dec 28:2020.10.07.307546. doi: 10.1101/2020.10.07.307546. bioRxiv. 2020. Update in: Nat Struct Mol Biol. 2021 May;28(5):404-408. doi: 10.1038/s41594-021-00593-7 PMID: 33052340 Free PMC article. Updated. Preprint.
Targeting the Synthetic Lethal Relationship between FOCAD and TUT7 Represents a Potential Therapeutic Opportunity for TUT4/7 Small-Molecule Inhibitors in Cancer.
Triboulet R, Sadykov K, Harvey DM, Wilson DM, Steinbaugh MJ, Mayo CB, Hawley D, Madanjian A, Fyfe C, Bracken C, Rivera-Rivera I, Ericsson A, Snyder AR, Knutson SK, Stein RL, Gibaja V, Ghosh S, Campbell RM. Triboulet R, et al. Among authors: fyfe c. Mol Cancer Ther. 2024 Dec 3;23(12):1779-1788. doi: 10.1158/1535-7163.MCT-24-0176. Mol Cancer Ther. 2024. PMID: 39235218
Parallel and High Throughput Reaction Monitoring with Computer Vision.
Barrington H, McCabe TJD, Donnachie K, Fyfe C, McFall A, Gladkikh M, McGuire J, Yan C, Reid M. Barrington H, et al. Among authors: fyfe c. Angew Chem Int Ed Engl. 2024 Aug 21:e202413395. doi: 10.1002/anie.202413395. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39166494
Novel Machine Learning HIV Intervention for Sexual and Gender Minority Young People Who Have Sex With Men (uTECH): Protocol for a Randomized Comparison Trial.
Holloway IW, Wu ESC, Boka C, Young N, Hong C, Fuentes K, Kärkkäinen K, Beikzadeh M, Avendaño A, Jauregui JC, Zhang A, Sevillano L, Fyfe C, Brisbin CD, Beltran RM, Cordero L, Parsons JT, Sarrafzadeh M. Holloway IW, et al. Among authors: fyfe c. JMIR Res Protoc. 2024 Aug 20;13:e58448. doi: 10.2196/58448. JMIR Res Protoc. 2024. PMID: 39163591 Free PMC article. Clinical Trial.
118 results