Silke J - Search Results

1

The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes.

Feltham R, Silke J. Feltham R, et al. Among authors: silke j. Cell Death Differ. 2017 Jul;24(7):1196-1204. doi: 10.1038/cdd.2017.67. Epub 2017 Jun 2. Cell Death Differ. 2017. PMID: 28574505 Free PMC article. Review.

2

Caspase inhibitors.

Ekert PG, Silke J, Vaux DL. Ekert PG, et al. Among authors: silke j. Cell Death Differ. 1999 Nov;6(11):1081-6. doi: 10.1038/sj.cdd.4400594. Cell Death Differ. 1999. PMID: 10578177 Review.

3

Till death do us part.

Ekert PG, Silke J. Ekert PG, et al. Among authors: silke j. Cell Death Differ. 2001 Jul;8(7):662-4. doi: 10.1038/sj.cdd.4400895. Cell Death Differ. 2001. PMID: 11464210 No abstract available.

4

Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.

Verhagen AM, Kratina TK, Hawkins CJ, Silke J, Ekert PG, Vaux DL. Verhagen AM, et al. Among authors: silke j. Cell Death Differ. 2007 Feb;14(2):348-57. doi: 10.1038/sj.cdd.4402001. Epub 2006 Jun 23. Cell Death Differ. 2007. PMID: 16794601

5

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.

Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J. Vince JE, et al. Among authors: silke j. Cell. 2007 Nov 16;131(4):682-93. doi: 10.1016/j.cell.2007.10.037. Cell. 2007. PMID: 18022363 Free article.

6

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

Sedelies KA, Ciccone A, Clarke CJ, Oliaro J, Sutton VR, Scott FL, Silke J, Susanto O, Green DR, Johnstone RW, Bird PI, Trapani JA, Waterhouse NJ. Sedelies KA, et al. Among authors: silke j. Cell Death Differ. 2008 Apr;15(4):708-17. doi: 10.1038/sj.cdd.4402300. Epub 2008 Jan 18. Cell Death Differ. 2008. PMID: 18202705

7

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.

Mace PD, Linke K, Feltham R, Schumacher FR, Smith CA, Vaux DL, Silke J, Day CL. Mace PD, et al. Among authors: silke j. J Biol Chem. 2008 Nov 14;283(46):31633-40. doi: 10.1074/jbc.M804753200. Epub 2008 Sep 10. J Biol Chem. 2008. PMID: 18784070 Free article.

8

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

Kaufmann T, Jost PJ, Pellegrini M, Puthalakath H, Gugasyan R, Gerondakis S, Cretney E, Smyth MJ, Silke J, Hakem R, Bouillet P, Mak TW, Dixit VM, Strasser A. Kaufmann T, et al. Among authors: silke j. Immunity. 2009 Jan 16;30(1):56-66. doi: 10.1016/j.immuni.2008.10.017. Immunity. 2009. PMID: 19119023 Free PMC article.

9

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.

Silke J, Brink R. Silke J, et al. Cell Death Differ. 2010 Jan;17(1):35-45. doi: 10.1038/cdd.2009.114. Cell Death Differ. 2010. PMID: 19680262 Review.

10

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC, Davidson AJ, Callus BA, Wong WW, Gentle IE, Carter H, Lee EF, Walczak H, Day CL, Vaux DL, Silke J. Vince JE, et al. Among authors: silke j. J Biol Chem. 2009 Dec 18;284(51):35906-15. doi: 10.1074/jbc.M109.072256. J Biol Chem. 2009. PMID: 19815541 Free PMC article.

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