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Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.
Lu J, Byrne N, Wang J, Bricogne G, Brown FK, Chobanian HR, Colletti SL, Di Salvo J, Thomas-Fowlkes B, Guo Y, Hall DL, Hadix J, Hastings NB, Hermes JD, Ho T, Howard AD, Josien H, Kornienko M, Lumb KJ, Miller MW, Patel SB, Pio B, Plummer CW, Sherborne BS, Sheth P, Souza S, Tummala S, Vonrhein C, Webb M, Allen SJ, Johnston JM, Weinglass AB, Sharma S, Soisson SM. Lu J, et al. Among authors: johnston jm. Nat Struct Mol Biol. 2017 Jul;24(7):570-577. doi: 10.1038/nsmb.3417. Epub 2017 Jun 5. Nat Struct Mol Biol. 2017. PMID: 28581512
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Petrilli WL, Adam GC, Erdmann RS, Abeywickrema P, Agnani V, Ai X, Baysarowich J, Byrne N, Caldwell JP, Chang W, DiNunzio E, Feng Z, Ford R, Ha S, Huang Y, Hubbard B, Johnston JM, Kavana M, Lisnock JM, Liang R, Lu J, Lu Z, Meng J, Orth P, Palyha O, Parthasarathy G, Salowe SP, Sharma S, Shipman J, Soisson SM, Strack AM, Youm H, Zhao K, Zink DL, Zokian H, Addona GH, Akinsanya K, Tata JR, Xiong Y, Imbriglio JE. Petrilli WL, et al. Among authors: johnston jm. Cell Chem Biol. 2020 Jan 16;27(1):32-40.e3. doi: 10.1016/j.chembiol.2019.10.002. Epub 2019 Oct 22. Cell Chem Biol. 2020. PMID: 31653597 Free article.
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Petrilli WL, Adam GC, Erdmann RS, Abeywickrema P, Agnani V, Ai X, Baysarowich J, Byrne N, Caldwell JP, Chang W, DiNunzio E, Feng Z, Ford R, Ha S, Huang Y, Hubbard B, Johnston JM, Kavana M, Lisnock JM, Liang R, Lu J, Lu Z, Meng J, Orth P, Palyha O, Parthasarathy G, Salowe SP, Sharma S, Shipman J, Soisson SM, Strack A, Youm H, Zhao K, Zink DL, Zokian H, Addona GH, Akinsanya K, Tata JR, Xiong Y, Imbriglio JE. Petrilli WL, et al. Among authors: johnston jm. Cell Chem Biol. 2021 Feb 18;28(2):243. doi: 10.1016/j.chembiol.2021.01.019. Cell Chem Biol. 2021. PMID: 33607006 Free article. No abstract available.
A non-canonical mechanism of GPCR activation.
Powers AS, Khan A, Paggi JM, Latorraca NR, Souza S, Di Salvo J, Lu J, Soisson SM, Johnston JM, Weinglass AB, Dror RO. Powers AS, et al. Among authors: johnston jm. Nat Commun. 2024 Nov 16;15(1):9938. doi: 10.1038/s41467-024-54103-6. Nat Commun. 2024. PMID: 39550377 Free PMC article.
Treatment of sleep-disordered breathing among children with myelomeningocele.
Stewart A, Rau S, Shellhaas RA, Woodward J, Hopson B, Arynchyna-Smith A, Shamblin I, Blount JP, Pascoe JE, Rozzelle CJ, Johnston JM, Maddox MH, Rocque BG. Stewart A, et al. Among authors: johnston jm. J Neurosurg Pediatr. 2024 Nov 1:1-5. doi: 10.3171/2024.8.PEDS24223. Online ahead of print. J Neurosurg Pediatr. 2024. PMID: 39486076
Global Partnerships in Neurosurgery: Mapping the Need.
Gupta S, Gomez MG, Johnston JM, Park KB. Gupta S, et al. Among authors: johnston jm. Neurosurg Clin N Am. 2024 Oct;35(4):489-498. doi: 10.1016/j.nec.2024.05.011. Epub 2024 Jul 25. Neurosurg Clin N Am. 2024. PMID: 39244321 Review.
Neurosurgical management of Myelomeningocele in premature infants: a case series.
Stewart A, Hale AT, Saccomano BW, Barkley AS, Hopson BD, Arynchyna-Smith A, Johnston JM, Rocque BG, Blount JP, Rozzelle CJ. Stewart A, et al. Among authors: johnston jm. Childs Nerv Syst. 2024 Nov;40(11):3609-3614. doi: 10.1007/s00381-024-06524-3. Epub 2024 Jul 20. Childs Nerv Syst. 2024. PMID: 39030337 Free PMC article.
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