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Page 1
Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.
Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA. Montero-Conde C, et al. Among authors: dupuy aj. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4951-E4960. doi: 10.1073/pnas.1702723114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584132 Free PMC article.
Mammalian germ-line transgenesis by transposition.
Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Dupuy AJ, et al. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4495-9. doi: 10.1073/pnas.062630599. Epub 2002 Mar 19. Proc Natl Acad Sci U S A. 2002. PMID: 11904379 Free PMC article.
A DNA transposon-based approach to validate oncogenic mutations in the mouse.
Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P. Su Q, et al. Among authors: dupuy aj. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19904-9. doi: 10.1073/pnas.0807785105. Epub 2008 Dec 8. Proc Natl Acad Sci U S A. 2008. PMID: 19064922 Free PMC article.
A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis.
Starr TK, Scott PM, Marsh BM, Zhao L, Than BL, O'Sullivan MG, Sarver AL, Dupuy AJ, Largaespada DA, Cormier RT. Starr TK, et al. Among authors: dupuy aj. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5765-70. doi: 10.1073/pnas.1018012108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21436051 Free PMC article.
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.
Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ; Australian Pancreatic Cancer Genome Initiative; Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, Rust AG, Adams DJ, Jenkins NA, Copeland NG. Mann KM, et al. Among authors: dupuy aj. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5934-41. doi: 10.1073/pnas.1202490109. Epub 2012 Mar 15. Proc Natl Acad Sci U S A. 2012. PMID: 22421440 Free PMC article.
A transposon-based analysis of gene mutations related to skin cancer development.
Quintana RM, Dupuy AJ, Bravo A, Casanova ML, Alameda JP, Page A, Sánchez-Viera M, Ramírez A, Navarro M. Quintana RM, et al. Among authors: dupuy aj. J Invest Dermatol. 2013 Jan;133(1):239-48. doi: 10.1038/jid.2012.245. Epub 2012 Jul 26. J Invest Dermatol. 2013. PMID: 22832494 Free article.
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.
Zanesi N, Balatti V, Riordan J, Burch A, Rizzotto L, Palamarchuk A, Cascione L, Lagana A, Dupuy AJ, Croce CM, Pekarsky Y. Zanesi N, et al. Among authors: dupuy aj. Blood. 2013 May 23;121(21):4355-8. doi: 10.1182/blood-2013-02-486035. Epub 2013 Apr 16. Blood. 2013. PMID: 23591791 Free PMC article.
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