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Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.
Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM. Fernández-Del-Río L, et al. Among authors: nag a. Free Radic Biol Med. 2017 Sep;110:176-187. doi: 10.1016/j.freeradbiomed.2017.06.006. Epub 2017 Jun 9. Free Radic Biol Med. 2017. PMID: 28603085 Free PMC article.
Coenzyme Q10 deficiencies: pathways in yeast and humans.
Awad AM, Bradley MC, Fernández-Del-Río L, Nag A, Tsui HS, Clarke CF. Awad AM, et al. Among authors: nag a. Essays Biochem. 2018 Jul 20;62(3):361-376. doi: 10.1042/EBC20170106. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 29980630 Free PMC article. Review.
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.
Widmeier E, Yu S, Nag A, Chung YW, Nakayama M, Fernández-Del-Río L, Hugo H, Schapiro D, Buerger F, Choi WI, Helmstädter M, Kim JW, Ryu JH, Lee MG, Clarke CF, Hildebrandt F, Gee HY. Widmeier E, et al. Among authors: nag a. J Am Soc Nephrol. 2020 Jun;31(6):1191-1211. doi: 10.1681/ASN.2019070756. Epub 2020 May 7. J Am Soc Nephrol. 2020. PMID: 32381600 Free PMC article.
Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice.
Widmeier E, Airik M, Hugo H, Schapiro D, Wedel J, Ghosh CC, Nakayama M, Schneider R, Awad AM, Nag A, Cho J, Schueler M, Clarke CF, Airik R, Hildebrandt F. Widmeier E, et al. Among authors: nag a. J Am Soc Nephrol. 2019 Mar;30(3):393-405. doi: 10.1681/ASN.2018060625. Epub 2019 Feb 8. J Am Soc Nephrol. 2019. PMID: 30737270 Free PMC article.
635 results