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The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM. Ignatius MS, et al. Cell Rep. 2017 Jun 13;19(11):2304-2318. doi: 10.1016/j.celrep.2017.05.061. Cell Rep. 2017. PMID: 28614716 Free PMC article.
Zebrafish as a model for cancer self-renewal.
Ignatius MS, Langenau DM. Ignatius MS, et al. Zebrafish. 2009 Dec;6(4):377-87. doi: 10.1089/zeb.2009.0610. Zebrafish. 2009. PMID: 19954344 Free PMC article.
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. Smith AC, et al. Among authors: ignatius ms. Blood. 2010 Apr 22;115(16):3296-303. doi: 10.1182/blood-2009-10-246488. Epub 2010 Jan 7. Blood. 2010. PMID: 20056790 Free PMC article.
Fluorescent imaging of cancer in zebrafish.
Ignatius MS, Langenau DM. Ignatius MS, et al. Methods Cell Biol. 2011;105:437-59. doi: 10.1016/B978-0-12-381320-6.00019-9. Methods Cell Biol. 2011. PMID: 21951542 Free PMC article.
Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma.
Chen EY, Dobrinski KP, Brown KH, Clagg R, Edelman E, Ignatius MS, Chen JY, Brockmann J, Nielsen GP, Ramaswamy S, Keller C, Lee C, Langenau DM. Chen EY, et al. Among authors: ignatius ms. PLoS Genet. 2013 Aug;9(8):e1003727. doi: 10.1371/journal.pgen.1003727. Epub 2013 Aug 29. PLoS Genet. 2013. PMID: 24009521 Free PMC article.
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Chen EY, et al. Among authors: ignatius ms. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5349-54. doi: 10.1073/pnas.1317731111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706870 Free PMC article.
Optimized cell transplantation using adult rag2 mutant zebrafish.
Tang Q, Abdelfattah NS, Blackburn JS, Moore JC, Martinez SA, Moore FE, Lobbardi R, Tenente IM, Ignatius MS, Berman JN, Liwski RS, Houvras Y, Langenau DM. Tang Q, et al. Among authors: ignatius ms. Nat Methods. 2014 Aug;11(8):821-4. doi: 10.1038/nmeth.3031. Epub 2014 Jul 20. Nat Methods. 2014. PMID: 25042784 Free PMC article.
30 results