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The G protein-coupled receptor GPR31 promotes membrane association of KRAS.
Fehrenbacher N, Tojal da Silva I, Ramirez C, Zhou Y, Cho KJ, Kuchay S, Shi J, Thomas S, Pagano M, Hancock JF, Bar-Sagi D, Philips MR. Fehrenbacher N, et al. Among authors: kuchay s. J Cell Biol. 2017 Aug 7;216(8):2329-2338. doi: 10.1083/jcb.201609096. Epub 2017 Jun 15. J Cell Biol. 2017. PMID: 28619714 Free PMC article.
Germline BAP1 mutations induce a Warburg effect.
Bononi A, Yang H, Giorgi C, Patergnani S, Pellegrini L, Su M, Xie G, Signorato V, Pastorino S, Morris P, Sakamoto G, Kuchay S, Gaudino G, Pass HI, Napolitano A, Pinton P, Jia W, Carbone M. Bononi A, et al. Among authors: kuchay s. Cell Death Differ. 2017 Oct;24(10):1694-1704. doi: 10.1038/cdd.2017.95. Epub 2017 Jun 30. Cell Death Differ. 2017. PMID: 28665402 Free PMC article.
BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M. Bononi A, et al. Among authors: kuchay s. Nature. 2017 Jun 22;546(7659):549-553. doi: 10.1038/nature22798. Epub 2017 Jun 14. Nature. 2017. PMID: 28614305 Free PMC article.
31 results