Marugan JJ - Search Results

1

Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.

Li R, Hao J, Fujiwara H, Xu M, Yang S, Dai S, Long Y, Swaroop M, Li C, Vu M, Marugan JJ, Ory DS, Zheng W. Li R, et al. Among authors: marugan jj. Assay Drug Dev Technol. 2017 May/Jun;15(4):154-166. doi: 10.1089/adt.2017.774. Assay Drug Dev Technol. 2017. PMID: 28631941 Free PMC article.

2

Multi-gram scale synthesis of FR180204.

Patnaik S, Dietz HC, Zheng W, Austin C, Marugan JJ. Patnaik S, et al. Among authors: marugan jj. J Org Chem. 2009 Nov 20;74(22):8870-3. doi: 10.1021/jo901835m. J Org Chem. 2009. PMID: 19852504 Free PMC article.

3

High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements.

Chen CZ, Kulakova L, Southall N, Marugan JJ, Galkin A, Austin CP, Herzberg O, Zheng W. Chen CZ, et al. Among authors: marugan jj. Antimicrob Agents Chemother. 2011 Feb;55(2):667-75. doi: 10.1128/AAC.00618-10. Epub 2010 Nov 15. Antimicrob Agents Chemother. 2011. PMID: 21078930 Free PMC article.

4

Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.

Marugan JJ, Zheng W, Motabar O, Southall N, Goldin E, Westbroek W, Stubblefield BK, Sidransky E, Aungst RA, Lea WA, Simeonov A, Leister W, Austin CP. Marugan JJ, et al. J Med Chem. 2011 Feb 24;54(4):1033-58. doi: 10.1021/jm1008902. Epub 2011 Jan 20. J Med Chem. 2011. PMID: 21250698 Free PMC article.

5

Discovery, synthesis, and biological evaluation of novel SMN protein modulators.

Xiao J, Marugan JJ, Zheng W, Titus S, Southall N, Cherry JJ, Evans M, Androphy EJ, Austin CP. Xiao J, et al. Among authors: marugan jj. J Med Chem. 2011 Sep 22;54(18):6215-33. doi: 10.1021/jm200497t. Epub 2011 Aug 19. J Med Chem. 2011. PMID: 21819082 Free PMC article.

6

A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide.

Motabar O, Goldin E, Leister W, Liu K, Southall N, Huang W, Marugan JJ, Sidransky E, Zheng W. Motabar O, et al. Among authors: marugan jj. Anal Bioanal Chem. 2012 Jan;402(2):731-9. doi: 10.1007/s00216-011-5496-z. Epub 2011 Oct 28. Anal Bioanal Chem. 2012. PMID: 22033823 Free PMC article.

7

Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.

Chen CZ, Sobczak K, Hoskins J, Southall N, Marugan JJ, Zheng W, Thornton CA, Austin CP. Chen CZ, et al. Among authors: marugan jj. Anal Bioanal Chem. 2012 Feb;402(5):1889-98. doi: 10.1007/s00216-011-5604-0. Epub 2012 Jan 5. Anal Bioanal Chem. 2012. PMID: 22218462 Free PMC article.

8

Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase.

Patnaik S, Zheng W, Choi JH, Motabar O, Southall N, Westbroek W, Lea WA, Velayati A, Goldin E, Sidransky E, Leister W, Marugan JJ. Patnaik S, et al. Among authors: marugan jj. J Med Chem. 2012 Jun 28;55(12):5734-48. doi: 10.1021/jm300063b. Epub 2012 Jun 8. J Med Chem. 2012. PMID: 22646221 Free PMC article.

9

A high-throughput sphingomyelinase assay using natural substrate.

Xu M, Liu K, Southall N, Marugan JJ, Remaley AT, Zheng W. Xu M, et al. Among authors: marugan jj. Anal Bioanal Chem. 2012 Aug;404(2):407-14. doi: 10.1007/s00216-012-6174-5. Epub 2012 Jun 19. Anal Bioanal Chem. 2012. PMID: 22710568 Free PMC article.

10

Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.

Krueger AB, Dehdashti SJ, Southall N, Marugan JJ, Ferrer M, Li X, Ford HL, Zheng W, Zhao R. Krueger AB, et al. Among authors: marugan jj. J Biomol Screen. 2013 Jan;18(1):85-96. doi: 10.1177/1087057112453936. Epub 2012 Jul 20. J Biomol Screen. 2013. PMID: 22820394 Free PMC article.

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