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Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.
Niemann CU, Mora-Jensen HI, Dadashian EL, Krantz F, Covey T, Chen SS, Chiorazzi N, Izumi R, Ulrich R, Lannutti BJ, Wiestner A, Herman SEM. Niemann CU, et al. Among authors: wiestner a. Clin Cancer Res. 2017 Oct 1;23(19):5814-5823. doi: 10.1158/1078-0432.CCR-17-0650. Epub 2017 Jun 23. Clin Cancer Res. 2017. PMID: 28645939 Free PMC article.
Autoreactive, cytotoxic T lymphocytes specific for peptides derived from normal B-cell differentiation antigens in healthy individuals and patients with B-cell malignancies.
Grube M, Rezvani K, Wiestner A, Fujiwara H, Sconocchia G, Melenhorst JJ, Hensel N, Marti GE, Kwak LW, Wilson W, Barrett JA. Grube M, et al. Among authors: wiestner a. Clin Cancer Res. 2004 Feb 1;10(3):1047-56. doi: 10.1158/1078-0432.ccr-03-0075. Clin Cancer Res. 2004. PMID: 14871984
Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation.
Pérez-Galán P, Mora-Jensen H, Weniger MA, Shaffer AL 3rd, Rizzatti EG, Chapman CM, Mo CC, Stennett LS, Rader C, Liu P, Raghavachari N, Stetler-Stevenson M, Yuan C, Pittaluga S, Maric I, Dunleavy KM, Wilson WH, Staudt LM, Wiestner A. Pérez-Galán P, et al. Among authors: wiestner a. Blood. 2011 Jan 13;117(2):542-52. doi: 10.1182/blood-2010-02-269514. Epub 2010 Oct 18. Blood. 2011. PMID: 20956803 Free PMC article. Clinical Trial.
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1.
Herishanu Y, Gibellini F, Njuguna N, Hazan-Halevy I, Farooqui M, Bern S, Keyvanfar K, Lee E, Wilson W, Wiestner A. Herishanu Y, et al. Among authors: wiestner a. Leuk Lymphoma. 2011 Sep;52(9):1758-69. doi: 10.3109/10428194.2011.569962. Epub 2011 Jun 8. Leuk Lymphoma. 2011. PMID: 21649540 Free PMC article.
Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma.
Weniger MA, Rizzatti EG, Pérez-Galán P, Liu D, Wang Q, Munson PJ, Raghavachari N, White T, Tweito MM, Dunleavy K, Ye Y, Wilson WH, Wiestner A. Weniger MA, et al. Among authors: wiestner a. Clin Cancer Res. 2011 Aug 1;17(15):5101-12. doi: 10.1158/1078-0432.CCR-10-3367. Epub 2011 Jun 28. Clin Cancer Res. 2011. PMID: 21712452 Free PMC article.
196 results