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171 results

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Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial.
Aggarwal SP, Zinman L, Simpson E, McKinley J, Jackson KE, Pinto H, Kaufman P, Conwit RA, Schoenfeld D, Shefner J, Cudkowicz M; Northeast and Canadian Amyotrophic Lateral Sclerosis consortia. Aggarwal SP, et al. Lancet Neurol. 2010 May;9(5):481-8. doi: 10.1016/S1474-4422(10)70068-5. Epub 2010 Apr 1. Lancet Neurol. 2010. PMID: 20363190 Free PMC article. Clinical Trial.
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS.
Shefner JM, Andrews JA, Genge A, Jackson C, Lechtzin N, Miller TM, Cockroft BM, Meng L, Wei J, Wolff AA, Malik FI, Bodkin C, Brooks BR, Caress J, Dionne A, Fee D, Goutman SA, Goyal NA, Hardiman O, Hayat G, Heiman-Patterson T, Heitzman D, Henderson RD, Johnston W, Karam C, Kiernan MC, Kolb SJ, Korngut L, Ladha S, Matte G, Mora JS, Needham M, Oskarsson B, Pattee GL, Pioro EP, Pulley M, Quan D, Rezania K, Schellenberg KL, Schultz D, Shoesmith C, Simmons Z, Statland J, Sultan S, Swenson A, Berg LHVD, Vu T, Vucic S, Weiss M, Whyte-Rayson A, Wymer J, Zinman L, Rudnicki SA. Shefner JM, et al. Among authors: dionne a. Amyotroph Lateral Scler Frontotemporal Degener. 2021 May;22(3-4):287-299. doi: 10.1080/21678421.2020.1822410. Epub 2020 Sep 24. Amyotroph Lateral Scler Frontotemporal Degener. 2021. PMID: 32969758 Free PMC article. Clinical Trial.
Rate of speech decline in individuals with amyotrophic lateral sclerosis.
Eshghi M, Yunusova Y, Connaghan KP, Perry BJ, Maffei MF, Berry JD, Zinman L, Kalra S, Korngut L, Genge A, Dionne A, Green JR. Eshghi M, et al. Among authors: dionne a. Sci Rep. 2022 Sep 20;12(1):15713. doi: 10.1038/s41598-022-19651-1. Sci Rep. 2022. PMID: 36127362 Free PMC article.
Distinct patterns of progressive gray and white matter degeneration in amyotrophic lateral sclerosis.
Ishaque A, Ta D, Khan M, Zinman L, Korngut L, Genge A, Dionne A, Briemberg H, Luk C, Yang YH, Beaulieu C, Emery D, Eurich DT, Frayne R, Graham S, Wilman A, Dupré N, Kalra S. Ishaque A, et al. Among authors: dionne a. Hum Brain Mapp. 2022 Apr 1;43(5):1519-1534. doi: 10.1002/hbm.25738. Epub 2021 Dec 15. Hum Brain Mapp. 2022. PMID: 34908212 Free PMC article.
Functional alterations in large-scale resting-state networks of amyotrophic lateral sclerosis: A multi-site study across Canada and the United States.
Bharti K, J Graham S, Benatar M, Briemberg H, Chenji S, Dupré N, Dionne A, Frayne R, Genge A, Korngut L, Luk C, Zinman L, Kalra S; Canadian ALS Neuroimaging Consortium (CALSNIC). Bharti K, et al. Among authors: dionne a. PLoS One. 2022 Jun 16;17(6):e0269154. doi: 10.1371/journal.pone.0269154. eCollection 2022. PLoS One. 2022. PMID: 35709100 Free PMC article.
Genetic testing for amyotrophic lateral sclerosis in Canada - an assessment of current practices.
Salmon K, Anoja N, Breiner A, Chum M, Dionne A, Dupré N, Fiander A, Fok D, Ghavanini A, Gosselin S, Izenberg A, Johnston W, Kalra S, Matte G, Melanson M, O'Connell C, Ritsma B, Schellenberg K, Shoesmith C, Tremblay S, Williams H, Genge A. Salmon K, et al. Among authors: dionne a. Amyotroph Lateral Scler Frontotemporal Degener. 2022 May;23(3-4):305-312. doi: 10.1080/21678421.2021.1980890. Epub 2021 Sep 27. Amyotroph Lateral Scler Frontotemporal Degener. 2022. PMID: 34569363
Defining cognitive impairment in amyotrophic lateral sclerosis: an evaluation of empirical approaches.
McMillan CT, Wuu J, Rascovsky K, Cosentino S, Grossman M, Elman L, Quinn C, Rosario L, Stark JH, Granit V, Briemberg H, Chenji S, Dionne A, Genge A, Johnston W, Korngut L, Shoesmith C, Zinman L; Canadian ALS Neuroimaging Consortium (CALSNIC); Kalra S, Benatar M. McMillan CT, et al. Among authors: dionne a. Amyotroph Lateral Scler Frontotemporal Degener. 2022 Nov;23(7-8):517-526. doi: 10.1080/21678421.2022.2039713. Epub 2022 Mar 7. Amyotroph Lateral Scler Frontotemporal Degener. 2022. PMID: 35253557 Free PMC article.
171 results