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Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system.
Hirsch D, Gaiser T, Merx K, Weingaertner S, Forster M, Hendricks A, Woenckhaus M, Schubert T, Hofheinz RD, Gencer D. Hirsch D, et al. J Cancer Res Clin Oncol. 2021 Jan;147(1):263-273. doi: 10.1007/s00432-020-03335-2. Epub 2020 Aug 9. J Cancer Res Clin Oncol. 2021. PMID: 32776177 Free PMC article.
LGR5 positivity defines stem-like cells in colorectal cancer.
Hirsch D, Barker N, McNeil N, Hu Y, Camps J, McKinnon K, Clevers H, Ried T, Gaiser T. Hirsch D, et al. Carcinogenesis. 2014 Apr;35(4):849-58. doi: 10.1093/carcin/bgt377. Epub 2013 Nov 26. Carcinogenesis. 2014. PMID: 24282287 Free PMC article.
The evolution of single cell-derived colorectal cancer cell lines is dominated by the continued selection of tumor-specific genomic imbalances, despite random chromosomal instability.
Wangsa D, Braun R, Schiefer M, Gertz EM, Bronder D, Quintanilla I, Padilla-Nash HM, Torres I, Hunn C, Warner L, Buishand FO, Hu Y, Hirsch D, Gaiser T, Camps J, Schwartz R, Schäffer AA, Heselmeyer-Haddad K, Ried T. Wangsa D, et al. Among authors: hirsch d. Carcinogenesis. 2018 Jul 30;39(8):993-1005. doi: 10.1093/carcin/bgy068. Carcinogenesis. 2018. PMID: 29800151 Free PMC article.
538 results