Theard P - Search Results

1

Protocol for modeling acquired resistance to targeted therapeutics in adherent and suspension cancer cell lines via in situ resistance assay.

Sealover NE, Hughes JM, Theard PL, Chatterjee D, Linke AJ, Finniff BA, Daley BR, Lewis RE, Kortum RL. Sealover NE, et al. Among authors: theard pl. STAR Protoc. 2024 Dec 20;5(4):103361. doi: 10.1016/j.xpro.2024.103361. Epub 2024 Oct 5. STAR Protoc. 2024. PMID: 39369385 Free PMC article.

2

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies.

Sealover NE, Theard PT, Hughes JM, Linke AJ, Daley BR, Kortum RL. Sealover NE, et al. Among authors: theard pt. iScience. 2023 Dec 11;27(1):108711. doi: 10.1016/j.isci.2023.108711. eCollection 2024 Jan 19. iScience. 2023. PMID: 38226159 Free PMC article.

3

Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation.

Yao X, Kaler M, Qu X, Kalidhindi RSR, Sviridov D, Dasseux A, Barr E, Keeran K, Jeffries KR, Yu ZX, Gao M, Gordon S, Barochia AV, Mills J, Shahid S, Weir NA, Kalchiem-Dekel O, Theard P, Playford MP, Stylianou M, Fitzgerald W, Remaley AT, Levine SJ. Yao X, et al. Among authors: theard p. J Allergy Clin Immunol. 2024 Apr;153(4):1010-1024.e14. doi: 10.1016/j.jaci.2023.11.917. Epub 2023 Dec 12. J Allergy Clin Immunol. 2024. PMID: 38092139

4

SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma.

Theard PL, Linke AJ, Sealover NE, Daley BR, Yang J, Cox K, Kortum RL. Theard PL, et al. Mol Oncol. 2024 Mar;18(3):641-661. doi: 10.1002/1878-0261.13564. Epub 2024 Jan 18. Mol Oncol. 2024. PMID: 38073064 Free PMC article.

5

SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis.

Theard PL, Linke AJ, Sealover NE, Daley BR, Yang J, Cox K, Kortum RL. Theard PL, et al. bioRxiv [Preprint]. 2023 Jun 29:2023.01.20.524989. doi: 10.1101/2023.01.20.524989. bioRxiv. 2023. Update in: Mol Oncol. 2024 Mar;18(3):641-661. doi: 10.1002/1878-0261.13564 PMID: 37425733 Free PMC article. Updated. Preprint.

6

In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies.

Sealover NE, Theard PL, Hughes JM, Linke AJ, Daley BR, Kortum RL. Sealover NE, et al. Among authors: theard pl. bioRxiv [Preprint]. 2023 Jun 28:2023.01.27.525958. doi: 10.1101/2023.01.27.525958. bioRxiv. 2023. Update in: iScience. 2023 Dec 11;27(1):108711. doi: 10.1016/j.isci.2023.108711 PMID: 36747633 Free PMC article. Updated. Preprint.

7

Eighth Annual DC Public Health Case Challenge: Addressing Infectious Diseases Using a Population Health Approach: Prevention and Control of Bacterial Sexually Transmitted Infections in Young Adults 18-24.

Geller A, Baciu A, Aidoo R, Alemayehu S, Andrada CI, Chen E, Dao A, Flattum-Riemers T, Forbes C, Gabriel A, Garcia JL, Gardiner C, Gonyea O, Graydon E, Henry-Smith C, Hughes K, Jammes C, Jones JH, Jeong EKG, Lammers J, Lu Y, Mason E, McIntyre M, Mencke J, Mielke S, Moye C, O'Brien E, Okoroajuzie A, Po M, Richmond M, Sadel J, Scott R, Sharma A, Southwick F, Theard P, Wanek A, Wasson K, Yo S. Geller A, et al. Among authors: theard p. NAM Perspect. 2022 Aug 8;2022:10.31478/202208a. doi: 10.31478/202208a. eCollection 2022. NAM Perspect. 2022. PMID: 36713774 Free PMC article. Review. No abstract available.

8

Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer.

Theard PL, Sheffels E, Sealover NE, Linke AJ, Pratico DJ, Kortum RL. Theard PL, et al. Elife. 2020 Sep 8;9:e58204. doi: 10.7554/eLife.58204. Elife. 2020. PMID: 32897190 Free PMC article.

9

Anchorage-independent growth conditions reveal a differential SOS2 dependence for transformation and survival in RAS-mutant cancer cells.

Sheffels E, Sealover NE, Theard PL, Kortum RL. Sheffels E, et al. Among authors: theard pl. Small GTPases. 2021 Jan;12(1):67-78. doi: 10.1080/21541248.2019.1611168. Epub 2019 May 7. Small GTPases. 2021. PMID: 31062644 Free PMC article.

10

High density lipoproteins and type 2 inflammatory biomarkers are negatively correlated in atopic asthmatics.

Barochia AV, Gordon EM, Kaler M, Cuento RA, Theard P, Figueroa DM, Yao X, Weir NA, Sampson ML, Stylianou M, Choy DF, Holweg CTJ, Remaley AT, Levine SJ. Barochia AV, et al. Among authors: theard p. J Lipid Res. 2017 Aug;58(8):1713-1721. doi: 10.1194/jlr.P077776. Epub 2017 Jun 27. J Lipid Res. 2017. PMID: 28655726 Free PMC article.

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