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Page 1
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.
Wienert B, Wyman SK, Richardson CD, Yeh CD, Akcakaya P, Porritt MJ, Morlock M, Vu JT, Kazane KR, Watry HL, Judge LM, Conklin BR, Maresca M, Corn JE. Wienert B, et al. Among authors: yeh cd. Science. 2019 Apr 19;364(6437):286-289. doi: 10.1126/science.aav9023. Epub 2019 Apr 18. Science. 2019. PMID: 31000663 Free PMC article.
Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations.
Cullot G, Aird EJ, Schlapansky MF, Yeh CD, van de Venn L, Vykhlyantseva I, Kreutzer S, Mailänder D, Lewków B, Klermund J, Montellese C, Biserni M, Aeschimann F, Vonarburg C, Gehart H, Cathomen T, Corn JE. Cullot G, et al. Among authors: yeh cd. Nat Biotechnol. 2024 Nov 27. doi: 10.1038/s41587-024-02488-6. Online ahead of print. Nat Biotechnol. 2024. PMID: 39604565
CRISPR off-target detection with DISCOVER-seq.
Wienert B, Wyman SK, Yeh CD, Conklin BR, Corn JE. Wienert B, et al. Among authors: yeh cd. Nat Protoc. 2020 May;15(5):1775-1799. doi: 10.1038/s41596-020-0309-5. Epub 2020 Apr 20. Nat Protoc. 2020. PMID: 32313254 Free PMC article.