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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.
Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, Spahn JE, Palmiotti CA, Siegel D, Ray AS, Cihlar T, Jordan R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: pyrc k. Sci Transl Med. 2017 Jun 28;9(396):eaal3653. doi: 10.1126/scitranslmed.aal3653. Sci Transl Med. 2017. PMID: 28659436 Free PMC article.
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda A, Plewka J, Rawski M, Mourão A, Zajko W, Siebenmorgen T, Kresik L, Lis K, Jones AN, Pachota M, Karim A, Hartman K, Nirwal S, Sonani R, Chykunova Y, Minia I, Mak P, Landthaler M, Nowotny M, Dubin G, Sattler M, Suder P, Popowicz GM, Pyrć K, Czarna A. Matsuda A, et al. Among authors: pyrc k. Nucleic Acids Res. 2024 Jun 24;52(11):6441-6458. doi: 10.1093/nar/gkae165. Nucleic Acids Res. 2024. PMID: 38499483 Free PMC article.
HTCC: Broad Range Inhibitor of Coronavirus Entry.
Milewska A, Kaminski K, Ciejka J, Kosowicz K, Zeglen S, Wojarski J, Nowakowska M, Szczubiałka K, Pyrc K. Milewska A, et al. Among authors: pyrc k. PLoS One. 2016 Jun 1;11(6):e0156552. doi: 10.1371/journal.pone.0156552. eCollection 2016. PLoS One. 2016. PMID: 27249425 Free PMC article.
Cat flu: Broad spectrum polymeric antivirals.
Synowiec A, Gryniuk I, Pachota M, Strzelec Ł, Roman O, Kłysik-Trzciańska K, Zając M, Drebot I, Gula K, Andruchowicz A, Rajfur Z, Szczubiałka K, Nowakowska M, Pyrc K. Synowiec A, et al. Among authors: pyrc k. Antiviral Res. 2019 Oct;170:104563. doi: 10.1016/j.antiviral.2019.104563. Epub 2019 Jul 17. Antiviral Res. 2019. PMID: 31325462
135 results