Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors.
Syenina A, Jagaraj CJ, Aman SA, Sridharan A, St John AL.
Syenina A, et al. Among authors: st john al.
Elife. 2015 Mar 18;4:e05291. doi: 10.7554/eLife.05291.
Elife. 2015.
PMID: 25783751
Free PMC article.
In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation are correlated with disease severity in human DENV patients (St John et al., 2013b). A major risk factor for developing …
In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation a …