Li H - Search Results

1

Pro-apoptotic cationic host defense peptides rich in lysine or arginine to reverse drug resistance by disrupting tumor cell membrane.

Dai Y, Cai X, Shi W, Bi X, Su X, Pan M, Li H, Lin H, Huang W, Qian H. Dai Y, et al. Among authors: li h. Amino Acids. 2017 Sep;49(9):1601-1610. doi: 10.1007/s00726-017-2453-y. Epub 2017 Jun 29. Amino Acids. 2017. PMID: 28664269

2

Synthesis and biological evaluation of novel aliphatic acid-conjugated antimicrobial peptides as potential agents with anti-tumor, multidrug resistance-reversing activity and enhanced stability.

Zhang B, Gu H, Shi W, Li H, Ma G, Chen X, Qian H, Lin H, Huang W, Ge L. Zhang B, et al. Among authors: li h. Amino Acids. 2017 Nov;49(11):1831-1841. doi: 10.1007/s00726-017-2482-6. Epub 2017 Aug 22. Amino Acids. 2017. PMID: 28831625

3

Discovery of novel free fatty acid receptor 1 agonists bearing triazole core via click chemistry.

Li Z, Yang J, Wang X, Li H, Liu C, Wang N, Huang W, Qian H. Li Z, et al. Among authors: li h. Bioorg Med Chem. 2016 Nov 1;24(21):5449-5454. doi: 10.1016/j.bmc.2016.08.068. Epub 2016 Sep 1. Bioorg Med Chem. 2016. PMID: 27624524

4

Design, synthesis and structure-activity relationship studies of novel free fatty acid receptor 1 agonists bearing amide linker.

Yang J, Li Z, Li H, Liu C, Wang N, Shi W, Liao C, Cai X, Huang W, Qian H. Yang J, et al. Among authors: li z, li h. Bioorg Med Chem. 2017 Apr 15;25(8):2445-2450. doi: 10.1016/j.bmc.2017.03.001. Epub 2017 Mar 2. Bioorg Med Chem. 2017. PMID: 28285923

5

Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

Li Z, Liu C, Xu X, Qiu Q, Su X, Dai Y, Yang J, Li H, Shi W, Liao C, Pan M, Huang W, Qian H. Li Z, et al. Among authors: li h. Eur J Med Chem. 2017 Sep 29;138:458-479. doi: 10.1016/j.ejmech.2017.07.001. Epub 2017 Jul 3. Eur J Med Chem. 2017. PMID: 28689096

6

Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.

Li J, Gu W, Bi X, Li H, Liao C, Liu C, Huang W, Qian H. Li J, et al. Among authors: li h. Bioorg Med Chem. 2017 Dec 15;25(24):6674-6679. doi: 10.1016/j.bmc.2017.11.010. Epub 2017 Nov 4. Bioorg Med Chem. 2017. PMID: 29146452

7

Design, synthesis, and biological evaluation of deuterated phenylpropionic acid derivatives as potent and long-acting free fatty acid receptor 1 agonists.

Li Z, Liu C, Xu X, Shi W, Li H, Dai Y, Cai X, Huang W, Qian H. Li Z, et al. Among authors: li h. Bioorg Chem. 2018 Feb;76:303-313. doi: 10.1016/j.bioorg.2017.12.012. Epub 2017 Dec 5. Bioorg Chem. 2018. PMID: 29223807

8

Design, synthesis and evaluation of a novel series of inhibitors reversing P-glycoprotein-mediated multidrug resistance.

Ghaleb H, Li H, Kairuki M, Qiu Q, Bi X, Liu C, Liao C, Li J, Hezam K, Huang W, Qian H. Ghaleb H, et al. Among authors: li j, li h. Chem Biol Drug Des. 2018 Sep;92(3):1708-1716. doi: 10.1111/cbdd.13338. Epub 2018 Jun 14. Chem Biol Drug Des. 2018. PMID: 29786944

9

pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications.

Li J, Liu Y, Li H, Shi W, Bi X, Qiu Q, Zhang B, Huang W, Qian H. Li J, et al. Among authors: li h. Biomater Sci. 2018 Nov 1;6(11):2998-3008. doi: 10.1039/c8bm00889b. Epub 2018 Sep 27. Biomater Sci. 2018. PMID: 30259038

10

Structure-Based Discovery of Pyrimidine Aminobenzene Derivatives as Potent Oral Reversal Agents against P-gp- and BCRP-Mediated Multidrug Resistance.

Qiu Q, Zou F, Li H, Shi W, Zhou D, Zhang P, Li T, Yin Z, Cai Z, Jiang Y, Huang W, Qian H. Qiu Q, et al. Among authors: li t, li h. J Med Chem. 2021 May 13;64(9):6179-6197. doi: 10.1021/acs.jmedchem.1c00246. Epub 2021 May 3. J Med Chem. 2021. PMID: 33938746

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