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Page 1
GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.
Hu X, Dallinga-Thie GM, Hovingh GK, Chang SY, Sandoval NP, Dang TLP, Fukamachi I, Miyashita K, Nakajima K, Murakami M, Fong LG, Ploug M, Young SG, Beigneux AP. Hu X, et al. J Clin Lipidol. 2017 Jul-Aug;11(4):964-971. doi: 10.1016/j.jacl.2017.05.017. Epub 2017 Jun 13. J Clin Lipidol. 2017. PMID: 28666713 Free PMC article.
An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.
Allan CM, Larsson M, Hu X, He C, Jung RS, Mapar A, Voss C, Miyashita K, Machida T, Murakami M, Nakajima K, Bensadoun A, Ploug M, Fong LG, Young SG, Beigneux AP. Allan CM, et al. Among authors: hu x. J Lipid Res. 2016 Oct;57(10):1889-1898. doi: 10.1194/jlr.M070813. Epub 2016 Aug 5. J Lipid Res. 2016. PMID: 27494936 Free PMC article.
Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.
Hu X, Sleeman MW, Miyashita K, Linton MF, Allan CM, He C, Larsson M, Tu Y, Sandoval NP, Jung RS, Mapar A, Machida T, Murakami M, Nakajima K, Ploug M, Fong LG, Young SG, Beigneux AP. Hu X, et al. J Lipid Res. 2017 Jan;58(1):208-215. doi: 10.1194/jlr.M072462. Epub 2016 Nov 15. J Lipid Res. 2017. PMID: 27875259 Free PMC article.
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.
Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG. Beigneux AP, et al. Among authors: hu x. N Engl J Med. 2017 Apr 27;376(17):1647-1658. doi: 10.1056/NEJMoa1611930. Epub 2017 Apr 5. N Engl J Med. 2017. PMID: 28402248 Free PMC article.
Macrophages release plasma membrane-derived particles rich in accessible cholesterol.
He C, Hu X, Weston TA, Jung RS, Sandhu J, Huang S, Heizer P, Kim J, Ellison R, Xu J, Kilburn M, Bensinger SJ, Riezman H, Tontonoz P, Fong LG, Jiang H, Young SG. He C, et al. Among authors: hu x. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8499-E8508. doi: 10.1073/pnas.1810724115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127022 Free PMC article.
NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.
He C, Hu X, Weston TA, Jung RS, Heizer P, Tu Y, Ellison R, Matsumoto K, Gerhardt H, Tontonoz P, Fong LG, Young SG, Jiang H. He C, et al. Among authors: hu x. Biochem Biophys Res Commun. 2018 Oct 12;504(4):899-902. doi: 10.1016/j.bbrc.2018.09.051. Epub 2018 Sep 15. Biochem Biophys Res Commun. 2018. PMID: 30224066 Free PMC article.
GPIHBP1 autoantibody syndrome during interferon β1a treatment.
Eguchi J, Miyashita K, Fukamachi I, Nakajima K, Murakami M, Kawahara Y, Yamashita T, Ohta Y, Abe K, Nakatsuka A, Mino M, Takase S, Okazaki H, Hegele RA, Ploug M, Hu X, Wada J, Young SG, Beigneux AP. Eguchi J, et al. Among authors: hu x. J Clin Lipidol. 2019 Jan-Feb;13(1):62-69. doi: 10.1016/j.jacl.2018.10.004. Epub 2018 Oct 24. J Clin Lipidol. 2019. PMID: 30514621 Free PMC article.
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