Szabó G - Search Results

1

Pharmacological comparison of traditional and non-traditional cannabinoid receptor 1 blockers in rodent models in vivo.

Varga B, Kassai F, Szabó G, Kovács P, Fischer J, Gyertyán I. Varga B, et al. Among authors: szabo g. Pharmacol Biochem Behav. 2017 Aug;159:24-35. doi: 10.1016/j.pbb.2017.06.012. Epub 2017 Jun 27. Pharmacol Biochem Behav. 2017. PMID: 28666894

2

New celecoxib derivatives as anti-inflammatory agents.

Szabó G, Fischer J, Kis-Varga A, Gyires K. Szabó G, et al. J Med Chem. 2008 Jan 10;51(1):142-7. doi: 10.1021/jm070821f. Epub 2007 Dec 12. J Med Chem. 2008. PMID: 18072726

3

Hit-to-lead optimization of pyrrolo[1,2-a]quinoxalines as novel cannabinoid type 1 receptor antagonists.

Szabó G, Kiss R, Páyer-Lengyel D, Vukics K, Szikra J, Baki A, Molnár L, Fischer J, Keseru GM. Szabó G, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3471-5. doi: 10.1016/j.bmcl.2009.05.010. Epub 2009 May 7. Bioorg Med Chem Lett. 2009. PMID: 19457667

4

Chemical and biological investigation of cyclopropyl containing diaryl-pyrazole-3-carboxamides as novel and potent cannabinoid type 1 receptor antagonists.

Szabó G, Varga B, Páyer-Lengyel D, Szemzo A, Erdélyi P, Vukics K, Szikra J, Hegyi E, Vastag M, Kiss B, Laszy J, Gyertyán I, Fischer J. Szabó G, et al. J Med Chem. 2009 Jul 23;52(14):4329-37. doi: 10.1021/jm900179y. J Med Chem. 2009. PMID: 19527048

5

Positive allosteric modulators for mGluR2 receptors: a medicinal chemistry perspective.

Szabó G, Keserű GM. Szabó G, et al. Curr Top Med Chem. 2014;14(15):1771-88. doi: 10.2174/1568026614666140826120716. Curr Top Med Chem. 2014. PMID: 25175883 Review.

6

Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs).

Szabó G, Kolok S, Orgován Z, Vastag M, Béni Z, Kóti J, Sághy K, Lévay GI, Greiner I, Keserű GM. Szabó G, et al. Eur J Med Chem. 2020 Jan 15;186:111881. doi: 10.1016/j.ejmech.2019.111881. Epub 2019 Nov 15. Eur J Med Chem. 2020. PMID: 31780081

7

Fragment Based Optimization of Metabotropic Glutamate Receptor 2 (mGluR2) Positive Allosteric Modulators in the Absence of Structural Information.

Szabó G, Túrós GI, Kolok S, Vastag M, Sánta Z, Dékány M, Lévay GI, Greiner I, Natsumi M, Tatsuya W, Keserű GM. Szabó G, et al. J Med Chem. 2019 Jan 10;62(1):234-246. doi: 10.1021/acs.jmedchem.8b00161. Epub 2018 Mar 14. J Med Chem. 2019. PMID: 29505715

8

Multiparameter Optimization of Naphthyridine Derivatives as Selective α5-GABA_A Receptor Negative Allosteric Modulators.

Szabó G, Éliás O, Erdélyi P, Potor A, Túrós GI, Károlyi BI, Varró G, Vaskó ÁG, Bata I, Kapus GL, Dohányos Z, Bobok AÁ, Fodor L, Thán M, Vastag M, Komlódi Z, Soukupné Kedves RÉ, Makó É, Süveges B, Greiner I. Szabó G, et al. J Med Chem. 2022 Jun 9;65(11):7876-7895. doi: 10.1021/acs.jmedchem.2c00414. Epub 2022 May 18. J Med Chem. 2022. PMID: 35584373

9

Fragment-Based Optimization of Dihydropyrazino-Benzimidazolones as Metabotropic Glutamate Receptor-2 Positive Allosteric Modulators against Migraine.

Szabó G, Erdélyi P, Kolok S, Vastag M, Halász AS, Kis-Varga I, Lévay GI, Béni Z, Kóti J, Greiner I, Keserű GM. Szabó G, et al. J Med Chem. 2021 Jun 24;64(12):8607-8620. doi: 10.1021/acs.jmedchem.1c00563. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34080424

10

Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an α5-GABAA receptor NAM.

Károlyi BI, Potor A, Kapus GL, Fodor L, Bobok A, Krámos B, Magdó I, Bata I, Szabó G. Károlyi BI, et al. Among authors: szabo g. Bioorg Med Chem Lett. 2023 Jan 15;80:129107. doi: 10.1016/j.bmcl.2022.129107. Epub 2022 Dec 19. Bioorg Med Chem Lett. 2023. PMID: 36549396

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