Poras H - Search Results

1

Substituted α-mercaptoketones, new types of specific neprilysin inhibitors.

Poras H, Patouret R, Leiris S, Ouimet T, Fournié-Zaluski MC, Roques BP. Poras H, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3883-3890. doi: 10.1016/j.bmcl.2017.06.050. Epub 2017 Jun 21. Bioorg Med Chem Lett. 2017. PMID: 28676269

2

Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP).

Inguimbert N, Coric P, Poras H, Meudal H, Teffot F, Fournié-Zaluski MC, Roques BP. Inguimbert N, et al. Among authors: poras h. J Med Chem. 2002 Mar 28;45(7):1477-86. doi: 10.1021/jm0005454. J Med Chem. 2002. PMID: 11906289

3

N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): In vitro and In vivo activities.

Inguimbert N, Poras H, Teffo F, Beslot F, Selkti M, Tomas A, Scalbert E, Bennejean C, Renard P, Fournié-Zaluski MC, Roques BP. Inguimbert N, et al. Among authors: poras h. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2001-5. doi: 10.1016/s0960-894x(02)00248-2. Bioorg Med Chem Lett. 2002. PMID: 12113828

4

Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin.

Menéndez L, Hidalgo A, Meana A, Poras H, Fournié-Zaluski MC, Roques BP, Baamonde A. Menéndez L, et al. Among authors: poras h. Eur J Pharmacol. 2008 Oct 31;596(1-3):50-5. doi: 10.1016/j.ejphar.2008.07.043. Epub 2008 Jul 30. Eur J Pharmacol. 2008. PMID: 18692494

5

Detection and quantification of botulinum neurotoxin type a by a novel rapid in vitro fluorimetric assay.

Poras H, Ouimet T, Orng SV, Fournié-Zaluski MC, Popoff MR, Roques BP. Poras H, et al. Appl Environ Microbiol. 2009 Jul;75(13):4382-90. doi: 10.1128/AEM.00091-09. Epub 2009 May 8. Appl Environ Microbiol. 2009. PMID: 19429547 Free PMC article.

6

Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250.

Fournié-Zaluski MC, Poras H, Roques BP, Nakajima Y, Ito K, Yoshimoto T. Fournié-Zaluski MC, et al. Among authors: poras h. Acta Crystallogr D Biol Crystallogr. 2009 Aug;65(Pt 8):814-22. doi: 10.1107/S090744490901779X. Epub 2009 Jul 17. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19622865 Free PMC article.

7

Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.

Ouimet T, Orng SV, Poras H, Gagnidze K, Devi LA, Fournié-Zaluski MC, Roques BP. Ouimet T, et al. Among authors: poras h. J Biol Chem. 2010 Nov 5;285(45):34390-400. doi: 10.1074/jbc.M110.120576. Epub 2010 Aug 31. J Biol Chem. 2010. PMID: 20807771 Free PMC article.

8

Pluripotentialities of a quenched fluorescent peptide substrate library: enzymatic detection, characterization, and isoenzymes differentiation.

Poras H, Ouimet T, Orng SV, Dangé E, Fournié-Zaluski MC, Roques BP. Poras H, et al. Anal Biochem. 2011 Dec 15;419(2):95-105. doi: 10.1016/j.ab.2011.08.016. Epub 2011 Aug 16. Anal Biochem. 2011. PMID: 21893023

9

Highly sensitive quenched fluorescent substrate of Legionella major secretory protein (msp) based on its structural analysis.

Poras H, Duquesnoy S, Dange E, Pinon A, Vialette M, Fournié-Zaluski MC, Ouimet T. Poras H, et al. J Biol Chem. 2012 Jun 8;287(24):20221-30. doi: 10.1074/jbc.M111.334334. Epub 2012 Apr 23. J Biol Chem. 2012. PMID: 22528499 Free PMC article.

10

Comparison of fluorigenic peptide substrates PL50, SNAPTide, and BoTest A/E for BoNT/A detection and quantification: exosite binding confers high-assay sensitivity.

Ouimet T, Duquesnoy S, Poras H, Fournié-Zaluski MC, Roques BP. Ouimet T, et al. Among authors: poras h. J Biomol Screen. 2013 Jul;18(6):726-35. doi: 10.1177/1087057113476089. Epub 2013 Feb 20. J Biomol Screen. 2013. PMID: 23427044

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