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Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.
Nelson CS, Cruz DV, Tran D, Bialas KM, Stamper L, Wu H, Gilbert M, Blair R, Alvarez X, Itell H, Chen M, Deshpande A, Chiuppesi F, Wussow F, Diamond DJ, Vandergrift N, Walter MR, Barry PA, Cohen-Wolkowiez M, Koelle K, Kaur A, Permar SR. Nelson CS, et al. Among authors: chiuppesi f. JCI Insight. 2017 Jul 6;2(13):e94002. doi: 10.1172/jci.insight.94002. eCollection 2017 Jul 6. JCI Insight. 2017. PMID: 28679960 Free PMC article.
Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex.
Wussow F, Chiuppesi F, Martinez J, Campo J, Johnson E, Flechsig C, Newell M, Tran E, Ortiz J, La Rosa C, Herrmann A, Longmate J, Chakraborty R, Barry PA, Diamond DJ. Wussow F, et al. Among authors: chiuppesi f. PLoS Pathog. 2014 Nov 20;10(11):e1004524. doi: 10.1371/journal.ppat.1004524. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25412505 Free PMC article.
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission.
Bialas KM, Tanaka T, Tran D, Varner V, Cisneros De La Rosa E, Chiuppesi F, Wussow F, Kattenhorn L, Macri S, Kunz EL, Estroff JA, Kirchherr J, Yue Y, Fan Q, Lauck M, O'Connor DH, Hall AH, Xavier A, Diamond DJ, Barry PA, Kaur A, Permar SR. Bialas KM, et al. Among authors: chiuppesi f. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13645-50. doi: 10.1073/pnas.1511526112. Epub 2015 Oct 19. Proc Natl Acad Sci U S A. 2015. PMID: 26483473 Free PMC article.
MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults.
La Rosa C, Longmate J, Martinez J, Zhou Q, Kaltcheva TI, Tsai W, Drake J, Carroll M, Wussow F, Chiuppesi F, Hardwick N, Dadwal S, Aldoss I, Nakamura R, Zaia JA, Diamond DJ. La Rosa C, et al. Among authors: chiuppesi f. Blood. 2017 Jan 5;129(1):114-125. doi: 10.1182/blood-2016-07-729756. Epub 2016 Oct 19. Blood. 2017. PMID: 27760761 Free PMC article. Clinical Trial.
Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.
Fan Q, Nelson CS, Bialas KM, Chiuppesi F, Amos J, Gurley TC, Marshall DJ, Eudailey J, Heimsath H, Himes J, Deshpande A, Walter MR, Wussow F, Diamond DJ, Barry PA, Moody MA, Kaur A, Permar SR. Fan Q, et al. Among authors: chiuppesi f. Clin Vaccine Immunol. 2017 May 5;24(5):e00510-16. doi: 10.1128/CVI.00510-16. Print 2017 May. Clin Vaccine Immunol. 2017. PMID: 28298291 Free PMC article.
Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice.
Chiuppesi F, Wussow F, Scharf L, Contreras H, Gao H, Meng Z, Nguyen J, Barry PA, Bjorkman PJ, Diamond DJ. Chiuppesi F, et al. PLoS One. 2017 Aug 16;12(8):e0183377. doi: 10.1371/journal.pone.0183377. eCollection 2017. PLoS One. 2017. PMID: 28813507 Free PMC article.
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