Palermo G - Search Results

1

Bayesian adaptive dose-escalation designs for simultaneously estimating the optimal and maximum safe dose based on safety and efficacy.

Yeung WY, Reigner B, Beyer U, Diack C, Sabanés Bové D, Palermo G, Jaki T. Yeung WY, et al. Among authors: palermo g. Pharm Stat. 2017 Nov;16(6):396-413. doi: 10.1002/pst.1818. Epub 2017 Jul 9. Pharm Stat. 2017. PMID: 28691311

2

Results and evaluation of a first-in-human study of RG7342, an mGlu5 positive allosteric modulator, utilizing Bayesian adaptive methods.

Sturm S, Delporte ML, Hadi S, Schobel S, Lindemann L, Weikert R, Jaeschke G, Derks M, Palermo G. Sturm S, et al. Among authors: palermo g. Br J Clin Pharmacol. 2018 Mar;84(3):445-455. doi: 10.1111/bcp.13466. Epub 2017 Dec 18. Br J Clin Pharmacol. 2018. PMID: 29096426 Free PMC article. Clinical Trial.

3

Preclinical and Early Clinical Profile of a Highly Selective and Potent Oral Inhibitor of Aldosterone Synthase (CYP11B2).

Bogman K, Schwab D, Delporte ML, Palermo G, Amrein K, Mohr S, De Vera Mudry MC, Brown MJ, Ferber P. Bogman K, et al. Among authors: palermo g. Hypertension. 2017 Jan;69(1):189-196. doi: 10.1161/HYPERTENSIONAHA.116.07716. Epub 2016 Nov 21. Hypertension. 2017. PMID: 27872236 Free PMC article.

4

Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of inclacumab in healthy Japanese and Caucasian subjects.

Morrison M, Palermo G, Schmitt C. Morrison M, et al. Among authors: palermo g. Eur J Clin Pharmacol. 2015 Nov;71(11):1365-74. doi: 10.1007/s00228-015-1938-4. Epub 2015 Sep 12. Eur J Clin Pharmacol. 2015. PMID: 26363899 Clinical Trial.

5

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.

Byrne LM, Rodrigues FB, Johnson EB, Wijeratne PA, De Vita E, Alexander DC, Palermo G, Czech C, Schobel S, Scahill RI, Heslegrave A, Zetterberg H, Wild EJ. Byrne LM, et al. Among authors: palermo g. Sci Transl Med. 2018 Sep 12;10(458):eaat7108. doi: 10.1126/scitranslmed.aat7108. Sci Transl Med. 2018. PMID: 30209243

6

Ranking the Predictive Power of Clinical and Biological Features Associated With Disease Progression in Huntington's Disease.

Ghazaleh N, Houghton R, Palermo G, Schobel SA, Wijeratne PA, Long JD. Ghazaleh N, et al. Among authors: palermo g. Front Neurol. 2021 May 20;12:678484. doi: 10.3389/fneur.2021.678484. eCollection 2021. Front Neurol. 2021. PMID: 34093422 Free PMC article.

7

Motor, cognitive, and functional declines contribute to a single progressive factor in early HD.

Schobel SA, Palermo G, Auinger P, Long JD, Ma S, Khwaja OS, Trundell D, Cudkowicz M, Hersch S, Sampaio C, Dorsey ER, Leavitt BR, Kieburtz KD, Sevigny JJ, Langbehn DR, Tabrizi SJ; TRACK-HD, COHORT, CARE-HD, and 2CARE Huntington Study Group Investigators. Schobel SA, et al. Among authors: palermo g. Neurology. 2017 Dec 12;89(24):2495-2502. doi: 10.1212/WNL.0000000000004743. Epub 2017 Nov 15. Neurology. 2017. PMID: 29142089 Free PMC article.

8

Tominersen in Adults with Manifest Huntington's Disease.

McColgan P, Thobhani A, Boak L, Schobel SA, Nicotra A, Palermo G, Trundell D, Zhou J, Schlegel V, Sanwald Ducray P, Hawellek DJ, Dorn J, Simillion C, Lindemann M, Wheelock V, Durr A, Anderson KE, Long JD, Wild EJ, Landwehrmeyer GB, Leavitt BR, Tabrizi SJ, Doody R; GENERATION HD1 Investigators. McColgan P, et al. Among authors: palermo g. N Engl J Med. 2023 Dec 7;389(23):2203-2205. doi: 10.1056/NEJMc2300400. N Engl J Med. 2023. PMID: 38055260 No abstract available.

9

The Multiplicity of Argonaute Complexes in Mammalian Cells.

Mauro M, Berretta M, Palermo G, Cavalieri V, La Rocca G. Mauro M, et al. Among authors: palermo g. J Pharmacol Exp Ther. 2023 Jan;384(1):1-9. doi: 10.1124/jpet.122.001158. Epub 2022 Jun 6. J Pharmacol Exp Ther. 2023. PMID: 35667689 Free PMC article. Review.

10

Diagnosis of hereditary ataxias: a real-world single center experience.

Meli A, Montano V, Palermo G, Fogli A, Rocchi A, Gerfo AL, Maltomini R, Cori L, Siniscalchi A, Bernardini C, Cecchi G, Siciliano G, Ceravolo R, Caligo MA, Mancuso M, Lopriore P. Meli A, et al. Among authors: palermo g. J Neurol. 2025 Jan 15;272(2):111. doi: 10.1007/s00415-024-12772-9. J Neurol. 2025. PMID: 39812846

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