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Aβ seeding potency peaks in the early stages of cerebral β-amyloidosis.
Ye L, Rasmussen J, Kaeser SA, Marzesco AM, Obermüller U, Mahler J, Schelle J, Odenthal J, Krüger C, Fritschi SK, Walker LC, Staufenbiel M, Baumann F, Jucker M. Ye L, et al. EMBO Rep. 2017 Sep;18(9):1536-1544. doi: 10.15252/embr.201744067. Epub 2017 Jul 12. EMBO Rep. 2017. PMID: 28701326 Free PMC article.
Aβ seeds resist inactivation by formaldehyde.
Fritschi SK, Cintron A, Ye L, Mahler J, Bühler A, Baumann F, Neumann M, Nilsson KP, Hammarström P, Walker LC, Jucker M. Fritschi SK, et al. Among authors: ye l. Acta Neuropathol. 2014 Oct;128(4):477-84. doi: 10.1007/s00401-014-1339-2. Epub 2014 Sep 6. Acta Neuropathol. 2014. PMID: 25193240 Free PMC article.
Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion.
Maier FC, Wehrl HF, Schmid AM, Mannheim JG, Wiehr S, Lerdkrai C, Calaminus C, Stahlschmidt A, Ye L, Burnet M, Stiller D, Sabri O, Reischl G, Staufenbiel M, Garaschuk O, Jucker M, Pichler BJ. Maier FC, et al. Among authors: ye l. Nat Med. 2014 Dec;20(12):1485-92. doi: 10.1038/nm.3734. Epub 2014 Nov 10. Nat Med. 2014. PMID: 25384087
Persistence of Aβ seeds in APP null mouse brain.
Ye L, Fritschi SK, Schelle J, Obermüller U, Degenhardt K, Kaeser SA, Eisele YS, Walker LC, Baumann F, Staufenbiel M, Jucker M. Ye L, et al. Nat Neurosci. 2015 Nov;18(11):1559-61. doi: 10.1038/nn.4117. Epub 2015 Sep 9. Nat Neurosci. 2015. PMID: 26352792
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.
Uhlmann RE, Rother C, Rasmussen J, Schelle J, Bergmann C, Ullrich Gavilanes EM, Fritschi SK, Buehler A, Baumann F, Skodras A, Al-Shaana R, Beschorner N, Ye L, Kaeser SA, Obermüller U, Christensen S, Kartberg F, Stavenhagen JB, Rahfeld JU, Cynis H, Qian F, Weinreb PH, Bussiere T, Walker LC, Staufenbiel M, Jucker M. Uhlmann RE, et al. Among authors: ye l. Nat Neurosci. 2020 Dec;23(12):1580-1588. doi: 10.1038/s41593-020-00737-w. Epub 2020 Nov 16. Nat Neurosci. 2020. PMID: 33199898 Free PMC article.
8,450 results