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372 results

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Page 1
Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
Morris EC, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, Grace S, Gilmour K, Workman S, Buckland K, Butler K, Chee R, Salama AD, Ibrahim H, Hara H, Duret C, Mavilio F, Male F, Bushman FD, Galy A, Burns SO, Gaspar HB, Thrasher AJ. Morris EC, et al. Among authors: bushman fd. Blood. 2017 Sep 14;130(11):1327-1335. doi: 10.1182/blood-2017-04-777136. Epub 2017 Jul 17. Blood. 2017. PMID: 28716862 Free PMC article.
Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.
Cavazzana-Calvo M, Payen E, Negre O, Wang G, Hehir K, Fusil F, Down J, Denaro M, Brady T, Westerman K, Cavallesco R, Gillet-Legrand B, Caccavelli L, Sgarra R, Maouche-Chrétien L, Bernaudin F, Girot R, Dorazio R, Mulder GJ, Polack A, Bank A, Soulier J, Larghero J, Kabbara N, Dalle B, Gourmel B, Socie G, Chrétien S, Cartier N, Aubourg P, Fischer A, Cornetta K, Galacteros F, Beuzard Y, Gluckman E, Bushman F, Hacein-Bey-Abina S, Leboulch P. Cavazzana-Calvo M, et al. Nature. 2010 Sep 16;467(7313):318-22. doi: 10.1038/nature09328. Nature. 2010. PMID: 20844535 Free PMC article.
Leucine zipper-based immunomagnetic purification of CAR T cells displaying multiple receptors.
James SE, Chen S, Ng BD, Fischman JS, Jahn L, Boardman AP, Rajagopalan A, Elias HK, Massa A, Manuele D, Nichols KB, Lazrak A, Lee N, Roche AM, McFarland AG, Petrichenko A, Everett JK, Bushman FD, Fei T, Kousa AI, Lemarquis AL, DeWolf S, Peled JU, Vardhana SA, Klebanoff CA, van den Brink MRM. James SE, et al. Among authors: bushman fd. Nat Biomed Eng. 2024 Dec;8(12):1592-1614. doi: 10.1038/s41551-024-01287-3. Epub 2024 Dec 23. Nat Biomed Eng. 2024. PMID: 39715901
Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs.
Ghosh S, Lahens N, Barekat K, Tang SY, Theken KN, Ricciotti E, Sengupta A, Joshi R, Bushman FD, Weljie A, Grosser T, FitzGerald GA. Ghosh S, et al. Among authors: bushman fd. bioRxiv [Preprint]. 2024 Dec 2:2024.11.26.625478. doi: 10.1101/2024.11.26.625478. bioRxiv. 2024. PMID: 39677795 Free PMC article. Preprint.
Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use.
Barekat K, Ricciotti E, Ghosh S, Herrmann C, Keat K, Assenmacher CA, Tanes C, Wilson N, Sengupta A, Das U, Joshi R, Ritchie M, Bittinger K, Weljie A, Cadwell K, Bushman FD, Wu G, FitzGerald GA. Barekat K, et al. Among authors: bushman fd. bioRxiv [Preprint]. 2024 Nov 26:2024.11.22.624882. doi: 10.1101/2024.11.22.624882. bioRxiv. 2024. PMID: 39651214 Free PMC article. Preprint.
Modulation of AAV transduction and integration targeting by topoisomerase poisons.
Kasimsetty A, Hwang Y, Everett JK, McFarland AG, Zolnoski SA, Lu T, Roche AM, Martínez-García PM, Sabatino DE, Bushman FD. Kasimsetty A, et al. Among authors: bushman fd. Mol Ther Methods Clin Dev. 2024 Oct 28;32(4):101364. doi: 10.1016/j.omtm.2024.101364. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39618424 Free PMC article.
TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function.
Dimitri AJ, Baxter AE, Chen GM, Hopkins CR, Rouin GT, Huang H, Kong W, Holliday CH, Wiebking V, Bartoszek R, Drury S, Dalton K, Koucky OM, Chen Z, Giles JR, Dils AT, Jung IY, O'Connor R, Collins S, Everett JK, Amses K, Sherrill-Mix S, Chandra A, Goldman N, Vahedi G, Jadlowsky JK, Young RM, Melenhorst JJ, Maude SL, Levine BL, Frey NV, Berger SL, Grupp SA, Porter DL, Herbst F, Porteus MH, Carty SA, Bushman FD, Weber EW, Wherry EJ, Jordan MS, Fraietta JA. Dimitri AJ, et al. Among authors: bushman fd. Sci Adv. 2024 Nov 15;10(46):eadp9371. doi: 10.1126/sciadv.adp9371. Epub 2024 Nov 13. Sci Adv. 2024. PMID: 39536093 Free PMC article.
Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia.
Voit RA, Liao X, Caulier A, Antoszewski M, Cohen B, Armant M, Lu HY, Fleming TJ, Kamal E, Wahlster L, Roche AM, Everett JK, Petrichenko A, Huang MM, Clarke W, Myers KC, Forester C, Perez-Atayde A, Bushman FD, Pellin D, Shimamura A, Williams DA, Sankaran VG. Voit RA, et al. Among authors: bushman fd. Cell Stem Cell. 2024 Nov 8:S1934-5909(24)00374-6. doi: 10.1016/j.stem.2024.10.012. Online ahead of print. Cell Stem Cell. 2024. PMID: 39532107 Free article.
Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy.
Chappell ME, Breda L, Tricoli L, Guerra A, Jarocha D, Castruccio Castracani C, Papp TE, Tanaka N, Hamilton N, Triebwasser MP, Ghiaccio V, Fedorky MT, Gollomp KL, Bochenek V, Roche AM, Everett JK, Cook EJ, Bushman FD, Teawtrakul N, Glentis S, Kattamis A, Mui BL, Tam YK, Weissman D, Abdulmalik O, Parhiz H, Rivella S. Chappell ME, et al. Among authors: bushman fd. Blood. 2024 Oct 10;144(15):1633-1645. doi: 10.1182/blood.2023023349. Blood. 2024. PMID: 38949981
372 results