Tanaka T - Search Results

1

Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells.

Fujikawa A, Sugawara H, Tanaka T, Matsumoto M, Kuboyama K, Suzuki R, Tanga N, Ogata A, Masumura M, Noda M. Fujikawa A, et al. Among authors: tanaka t. Sci Rep. 2017 Jul 17;7(1):5609. doi: 10.1038/s41598-017-05931-8. Sci Rep. 2017. PMID: 28717188 Free PMC article.

2

Discovery of novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as human chymase inhibitors using structure-based drug design.

Tanaka T, Sugawara H, Maruoka H, Imajo S, Muto T. Tanaka T, et al. Bioorg Med Chem. 2013 Jul 15;21(14):4233-49. doi: 10.1016/j.bmc.2013.04.079. Epub 2013 May 9. Bioorg Med Chem. 2013. PMID: 23719288

3

Structure-based design, synthesis, and binding mode analysis of novel and potent chymase inhibitors.

Futamura-Takahashi J, Tanaka T, Sugawara H, Iwashita S, Imajo S, Oyama Y, Muto T. Futamura-Takahashi J, et al. Among authors: tanaka t. Bioorg Med Chem Lett. 2018 Jan 15;28(2):188-192. doi: 10.1016/j.bmcl.2017.11.031. Epub 2017 Nov 16. Bioorg Med Chem Lett. 2018. PMID: 29191554

4

Pharmacokinetic/pharmacodynamic analyses of chymase inhibitor SUN13834 in NC/Nga mice and prediction of effective dosage for atopic dermatitis patients.

Ogata A, Fujieda Y, Terakawa M, Muto T, Tanaka T, Maruoka H, Nagahira K, Fukuda Y, Tomimori Y, Watanabe N. Ogata A, et al. Among authors: tanaka t. Int Immunopharmacol. 2011 Oct;11(10):1628-32. doi: 10.1016/j.intimp.2011.05.025. Epub 2011 Jun 12. Int Immunopharmacol. 2011. PMID: 21642018

5

Oral chymase inhibitor SUN13834 ameliorates skin inflammation as well as pruritus in mouse model for atopic dermatitis.

Terakawa M, Fujieda Y, Tomimori Y, Muto T, Tanaka T, Maruoka H, Nagahira K, Ogata A, Nakatsuka T, Fukuda Y. Terakawa M, et al. Among authors: tanaka t. Eur J Pharmacol. 2008 Dec 28;601(1-3):186-91. doi: 10.1016/j.ejphar.2008.10.040. Epub 2008 Oct 29. Eur J Pharmacol. 2008. PMID: 18996112

6

Discovery and in vivo effects of novel human natriuretic peptide receptor A (NPR-A) agonists with improved activity for rat NPR-A.

Iwaki T, Tanaka T, Miyazaki K, Suzuki Y, Okamura Y, Yamaki A, Iwanami M, Morozumi N, Furuya M, Oyama Y. Iwaki T, et al. Among authors: tanaka t. Bioorg Med Chem. 2017 Dec 15;25(24):6680-6694. doi: 10.1016/j.bmc.2017.11.006. Epub 2017 Nov 6. Bioorg Med Chem. 2017. PMID: 29153628

7

Discovery and SAR of a novel series of Natriuretic Peptide Receptor-A (NPR-A) agonists.

Iwaki T, Nakamura Y, Tanaka T, Ogawa Y, Iwamoto O, Okamura Y, Kawase Y, Furuya M, Oyama Y, Nagayama T. Iwaki T, et al. Among authors: tanaka t. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4904-4907. doi: 10.1016/j.bmcl.2017.09.028. Epub 2017 Sep 18. Bioorg Med Chem Lett. 2017. PMID: 28958620

8

Discovery and dimeric approach of novel Natriuretic Peptide Receptor A (NPR-A) agonists.

Iwaki T, Oyama Y, Tomoo T, Tanaka T, Okamura Y, Sugiyama M, Yamaki A, Furuya M. Iwaki T, et al. Among authors: tanaka t. Bioorg Med Chem. 2017 Mar 15;25(6):1762-1769. doi: 10.1016/j.bmc.2017.01.026. Epub 2017 Jan 28. Bioorg Med Chem. 2017. PMID: 28190653

9

Development of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as orally active human chymase inhibitors.

Maruoka H, Muto T, Tanaka T, Imajo S, Tomimori Y, Fukuda Y, Nakatsuka T. Maruoka H, et al. Among authors: tanaka t. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3435-9. doi: 10.1016/j.bmcl.2007.03.085. Epub 2007 Mar 30. Bioorg Med Chem Lett. 2007. PMID: 17434735

10

Identification of 6-substituted 4-arylsulfonyl-1,4-diazepane-2,5-diones as a novel scaffold for human chymase inhibitors.

Tanaka T, Muto T, Maruoka H, Imajo S, Fukami H, Tomimori Y, Fukuda Y, Nakatsuka T. Tanaka T, et al. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3431-4. doi: 10.1016/j.bmcl.2007.03.038. Epub 2007 Mar 16. Bioorg Med Chem Lett. 2007. PMID: 17419055

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