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The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia.
Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, Tabeling C, Reppe K, Meixenberger K, Dorhoi A, Ma J, Holmes A, Trendelenburg G, Heimesaat MM, Bereswill S, van der Linden M, Tschopp J, Mitchell TJ, Suttorp N, Opitz B. Witzenrath M, et al. J Immunol. 2011 Jul 1;187(1):434-40. doi: 10.4049/jimmunol.1003143. Epub 2011 Jun 6. J Immunol. 2011. PMID: 21646297
Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction.
Wang L, Yin J, Nickles HT, Ranke H, Tabuchi A, Hoffmann J, Tabeling C, Barbosa-Sicard E, Chanson M, Kwak BR, Shin HS, Wu S, Isakson BE, Witzenrath M, de Wit C, Fleming I, Kuppe H, Kuebler WM. Wang L, et al. Among authors: witzenrath m. J Clin Invest. 2012 Nov;122(11):4218-30. doi: 10.1172/JCI59176. Epub 2012 Oct 24. J Clin Invest. 2012. PMID: 23093775 Free PMC article.
Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness.
Tabeling C, Scheer H, Schönrock SM, Runge F, Gutbier B, Lienau J, Hamelmann E, Opitz B, Suttorp N, Mayer K, Behrens GM, Tschernig T, Witzenrath M. Tabeling C, et al. Among authors: witzenrath m. Am J Respir Cell Mol Biol. 2014 May;50(5):903-11. doi: 10.1165/rcmb.2013-0333OC. Am J Respir Cell Mol Biol. 2014. PMID: 24279792
288 results