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Network analyses identify liver-specific targets for treating liver diseases.
Lee S, Zhang C, Liu Z, Klevstig M, Mukhopadhyay B, Bergentall M, Cinar R, Ståhlman M, Sikanic N, Park JK, Deshmukh S, Harzandi AM, Kuijpers T, Grøtli M, Elsässer SJ, Piening BD, Snyder M, Smith U, Nielsen J, Bäckhed F, Kunos G, Uhlen M, Boren J, Mardinoglu A. Lee S, et al. Among authors: grotli m. Mol Syst Biol. 2017 Aug 21;13(8):938. doi: 10.15252/msb.20177703. Mol Syst Biol. 2017. PMID: 28827398 Free PMC article.
Drug Repositioning for Effective Prostate Cancer Treatment.
Turanli B, Grøtli M, Boren J, Nielsen J, Uhlen M, Arga KY, Mardinoglu A. Turanli B, et al. Among authors: grotli m. Front Physiol. 2018 May 15;9:500. doi: 10.3389/fphys.2018.00500. eCollection 2018. Front Physiol. 2018. PMID: 29867548 Free PMC article. Review.
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.
Li X, Kim W, Arif M, Gao C, Hober A, Kotol D, Strandberg L, Forsström B, Sivertsson Å, Oksvold P, Turkez H, Grøtli M, Sato Y, Kume H, Ogawa S, Boren J, Nielsen J, Uhlen M, Zhang C, Mardinoglu A. Li X, et al. Among authors: grotli m. Cancers (Basel). 2021 Jan 19;13(2):348. doi: 10.3390/cancers13020348. Cancers (Basel). 2021. PMID: 33478099 Free PMC article.
Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.
Nain-Perez A, Foller Füchtbauer A, Håversen L, Lulla A, Gao C, Matic J, Monjas L, Rodríguez A, Brear P, Kim W, Hyvönen M, Borén J, Mardinoglu A, Uhlen M, Grøtli M. Nain-Perez A, et al. Among authors: grotli m. Eur J Med Chem. 2022 Apr 15;234:114270. doi: 10.1016/j.ejmech.2022.114270. Epub 2022 Mar 8. Eur J Med Chem. 2022. PMID: 35290845 Free article.
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase.
Battisti UM, Gao C, Nilsson O, Akladios F, Lulla A, Bogucka A, Nain-Perez A, Håversen L, Kim W, Boren J, Hyvönen M, Uhlen M, Mardinoglu A, Grøtli M. Battisti UM, et al. Among authors: grotli m. Chembiochem. 2023 Jan 3;24(1):e202200339. doi: 10.1002/cbic.202200339. Epub 2022 Nov 9. Chembiochem. 2023. PMID: 36250581 Free PMC article.
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, Kim W, Yang H, Bayram C, Bolat I, Kiliclioglu M, Yuksel N, Tozlu OO, Zhang C, Sebhaoui J, Iqbal S, Shoaie S, Hacimuftuoglu A, Yildirim S, Turkez H, Uhlen M, Boren J, Mardinoglu A, Grøtli M. Battisti UM, et al. Among authors: grotli m. Nutrients. 2023 Jan 22;15(3):577. doi: 10.3390/nu15030577. Nutrients. 2023. PMID: 36771285 Free PMC article.
95 results