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Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers.
Anthony NG, Baiget J, Berretta G, Boyd M, Breen D, Edwards J, Gamble C, Gray AI, Harvey AL, Hatziieremia S, Ho KH, Huggan JK, Lang S, Llona-Minguez S, Luo JL, McIntosh K, Paul A, Plevin RJ, Robertson MN, Scott R, Suckling CJ, Sutcliffe OB, Young LC, Mackay SP. Anthony NG, et al. J Med Chem. 2017 Aug 24;60(16):7043-7066. doi: 10.1021/acs.jmedchem.7b00484. Epub 2017 Aug 15. J Med Chem. 2017. PMID: 28737909 Free PMC article.
DNA binding of a short lexitropsin.
Anthony NG, Fox KR, Johnston BF, Khalaf AI, Mackay SP, McGroarty IS, Parkinson JA, Skellern GG, Suckling CJ, Waigh RD. Anthony NG, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1353-6. doi: 10.1016/j.bmcl.2003.11.068. Bioorg Med Chem Lett. 2004. PMID: 14980697
Synthesis and antimicrobial activity of some netropsin analogues.
Khalaf AI, Ebrahimabadi AH, Drummond AJ, Anthony NG, Mackay SP, Suckling CJ, Waigh RD. Khalaf AI, et al. Among authors: anthony ng. Org Biomol Chem. 2004 Nov 7;2(21):3119-27. doi: 10.1039/B408386P. Epub 2004 Oct 6. Org Biomol Chem. 2004. PMID: 15505717
Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups.
Anthony NG, Breen D, Clarke J, Donoghue G, Drummond AJ, Ellis EM, Gemmell CG, Helesbeux JJ, Hunter IS, Khalaf AI, Mackay SP, Parkinson JA, Suckling CJ, Waigh RD. Anthony NG, et al. J Med Chem. 2007 Nov 29;50(24):6116-25. doi: 10.1021/jm070831g. Epub 2007 Oct 26. J Med Chem. 2007. PMID: 17960927
Identification of 2-aminothiazole-4-carboxylate derivatives active against Mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH.
Al-Balas Q, Anthony NG, Al-Jaidi B, Alnimr A, Abbott G, Brown AK, Taylor RC, Besra GS, McHugh TD, Gillespie SH, Johnston BF, Mackay SP, Coxon GD. Al-Balas Q, et al. Among authors: anthony ng. PLoS One. 2009;4(5):e5617. doi: 10.1371/journal.pone.0005617. Epub 2009 May 19. PLoS One. 2009. PMID: 19440303 Free PMC article.
170 results