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Spatio-temporal simulation of first pass drug perfusion in the liver.
Schwen LO, Krauss M, Niederalt C, Gremse F, Kiessling F, Schenk A, Preusser T, Kuepfer L. Schwen LO, et al. Among authors: kuepfer l. PLoS Comput Biol. 2014 Mar 13;10(3):e1003499. doi: 10.1371/journal.pcbi.1003499. eCollection 2014 Mar. PLoS Comput Biol. 2014. PMID: 24625393 Free PMC article.
The virtual liver: state of the art and future perspectives.
Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy P, Häussinger D, Hammad S, Hoehme S, Holzhütter HG, Klingmüller U, Kuepfer L, Timmer J, Zerial M, Hengstler JG. Drasdo D, et al. Among authors: kuepfer l. Arch Toxicol. 2014 Dec;88(12):2071-5. doi: 10.1007/s00204-014-1384-6. Arch Toxicol. 2014. PMID: 25331938 No abstract available.
Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations.
Schwen LO, Schenk A, Kreutz C, Timmer J, Bartolomé Rodríguez MM, Kuepfer L, Preusser T. Schwen LO, et al. Among authors: kuepfer l. PLoS One. 2015 Jul 29;10(7):e0133653. doi: 10.1371/journal.pone.0133653. eCollection 2015. PLoS One. 2015. PMID: 26222615 Free PMC article.
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.
Ghallab A, Cellière G, Henkel SG, Driesch D, Hoehme S, Hofmann U, Zellmer S, Godoy P, Sachinidis A, Blaszkewicz M, Reif R, Marchan R, Kuepfer L, Häussinger D, Drasdo D, Gebhardt R, Hengstler JG. Ghallab A, et al. Among authors: kuepfer l. J Hepatol. 2016 Apr;64(4):860-71. doi: 10.1016/j.jhep.2015.11.018. Epub 2015 Nov 27. J Hepatol. 2016. PMID: 26639393 Free article.
Zonated quantification of steatosis in an entire mouse liver.
Schwen LO, Homeyer A, Schwier M, Dahmen U, Dirsch O, Schenk A, Kuepfer L, Preusser T, Schenk A. Schwen LO, et al. Among authors: kuepfer l. Comput Biol Med. 2016 Jun 1;73:108-18. doi: 10.1016/j.compbiomed.2016.04.004. Epub 2016 Apr 11. Comput Biol Med. 2016. PMID: 27104496
62 results