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PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
Mzoughi S, Zhang J, Hequet D, Teo SX, Fang H, Xing QR, Bezzi M, Seah MKY, Ong SLM, Shin EM, Wollmann H, Wong ESM, Al-Haddawi M, Stewart CL, Tergaonkar V, Loh YH, Dunn NR, Messerschmidt DM, Guccione E. Mzoughi S, et al. Among authors: stewart cl. Nat Genet. 2017 Sep;49(9):1354-1363. doi: 10.1038/ng.3922. Epub 2017 Jul 24. Nat Genet. 2017. PMID: 28740264
The imprinted gene Magel2 regulates normal circadian output.
Kozlov SV, Bogenpohl JW, Howell MP, Wevrick R, Panda S, Hogenesch JB, Muglia LJ, Van Gelder RN, Herzog ED, Stewart CL. Kozlov SV, et al. Among authors: stewart cl. Nat Genet. 2007 Oct;39(10):1266-72. doi: 10.1038/ng2114. Epub 2007 Sep 23. Nat Genet. 2007. PMID: 17893678
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
Chojnowski A, Ong PF, Wong ES, Lim JS, Mutalif RA, Navasankari R, Dutta B, Yang H, Liow YY, Sze SK, Boudier T, Wright GD, Colman A, Burke B, Stewart CL, Dreesen O. Chojnowski A, et al. Among authors: stewart cl. Elife. 2015 Aug 27;4:e07759. doi: 10.7554/eLife.07759. Elife. 2015. PMID: 26312502 Free PMC article.
The nuclear lamins: flexibility in function.
Burke B, Stewart CL. Burke B, et al. Among authors: stewart cl. Nat Rev Mol Cell Biol. 2013 Jan;14(1):13-24. doi: 10.1038/nrm3488. Epub 2012 Dec 5. Nat Rev Mol Cell Biol. 2013. PMID: 23212477 Review.
Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.
Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL. Hernandez L, et al. Among authors: stewart cl. Dev Cell. 2010 Sep 14;19(3):413-25. doi: 10.1016/j.devcel.2010.08.013. Dev Cell. 2010. PMID: 20833363 Free PMC article.
335 results