Pasquale EB - Search Results

1

Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.

Lechtenberg BC, Mace PD, Sessions EH, Williamson R, Stalder R, Wallez Y, Roth GP, Riedl SJ, Pasquale EB. Lechtenberg BC, et al. Among authors: pasquale eb. ACS Med Chem Lett. 2017 Jun 12;8(7):726-731. doi: 10.1021/acsmedchemlett.7b00127. eCollection 2017 Jul 13. ACS Med Chem Lett. 2017. PMID: 28740606 Free PMC article.

2

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors.

Noberini R, Koolpe M, Peddibhotla S, Dahl R, Su Y, Cosford ND, Roth GP, Pasquale EB. Noberini R, et al. Among authors: pasquale eb. J Biol Chem. 2008 Oct 24;283(43):29461-72. doi: 10.1074/jbc.M804103200. Epub 2008 Aug 26. J Biol Chem. 2008. PMID: 18728010 Free PMC article.

3

The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.

Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB. Roselli S, et al. Among authors: pasquale eb. Cell Signal. 2010 Nov;22(11):1745-52. doi: 10.1016/j.cellsig.2010.06.015. Epub 2010 Jul 24. Cell Signal. 2010. PMID: 20603213 Free PMC article.

4

The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.

Wang L, Vervoort V, Wallez Y, Coré N, Cremer H, Pasquale EB. Wang L, et al. Among authors: pasquale eb. J Neurosci. 2010 Sep 29;30(39):13201-10. doi: 10.1523/JNEUROSCI.3289-10.2010. J Neurosci. 2010. PMID: 20881139 Free PMC article.

5

SHEP1 partners with CasL to promote marginal zone B-cell maturation.

Browne CD, Hoefer MM, Chintalapati SK, Cato MH, Wallez Y, Ostertag DV, Pasquale EB, Rickert RC. Browne CD, et al. Among authors: pasquale eb. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18944-9. doi: 10.1073/pnas.1007558107. Epub 2010 Oct 18. Proc Natl Acad Sci U S A. 2010. PMID: 20956287 Free PMC article.

6

NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.

Mace PD, Wallez Y, Dobaczewska MK, Lee JJ, Robinson H, Pasquale EB, Riedl SJ. Mace PD, et al. Among authors: pasquale eb. Nat Struct Mol Biol. 2011 Nov 13;18(12):1381-7. doi: 10.1038/nsmb.2152. Nat Struct Mol Biol. 2011. PMID: 22081014 Free PMC article.

7

Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells.

Wang S, Placzek WJ, Stebbins JL, Mitra S, Noberini R, Koolpe M, Zhang Z, Dahl R, Pasquale EB, Pellecchia M. Wang S, et al. Among authors: pasquale eb. J Med Chem. 2012 Mar 8;55(5):2427-36. doi: 10.1021/jm201743s. Epub 2012 Feb 27. J Med Chem. 2012. PMID: 22329578 Free PMC article.

8

Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor.

Lamberto I, Qin H, Noberini R, Premkumar L, Bourgin C, Riedl SJ, Song J, Pasquale EB. Lamberto I, et al. Among authors: pasquale eb. Biochem J. 2012 Jul 1;445(1):47-56. doi: 10.1042/BJ20120408. Biochem J. 2012. PMID: 22489865 Free PMC article.

9

NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.

Wallez Y, Mace PD, Pasquale EB, Riedl SJ. Wallez Y, et al. Among authors: pasquale eb. Genes Cancer. 2012 May;3(5-6):382-93. doi: 10.1177/1947601912460050. Genes Cancer. 2012. PMID: 23226576 Free PMC article.

10

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.

Mace PD, Wallez Y, Egger MF, Dobaczewska MK, Robinson H, Pasquale EB, Riedl SJ. Mace PD, et al. Among authors: pasquale eb. Nat Commun. 2013;4:1681. doi: 10.1038/ncomms2687. Nat Commun. 2013. PMID: 23575685 Free PMC article.

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