Decker AM - Search Results

1

Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists.

Kormos CM, Ondachi PW, Runyon SP, Thomas JB, Mascarella SW, Decker AM, Navarro HA, Carroll FI. Kormos CM, et al. Among authors: decker am. ACS Med Chem Lett. 2017 May 25;8(7):742-745. doi: 10.1021/acsmedchemlett.7b00115. eCollection 2017 Jul 13. ACS Med Chem Lett. 2017. PMID: 28740609 Free PMC article.

2

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction.

Carroll FI, Blough BE, Abraham P, Mills AC, Holleman JA, Wolckenhauer SA, Decker AM, Landavazo A, McElroy KT, Navarro HA, Gatch MB, Forster MJ. Carroll FI, et al. Among authors: decker am. J Med Chem. 2009 Nov 12;52(21):6768-81. doi: 10.1021/jm901189z. J Med Chem. 2009. PMID: 19821577

3

Truncated Orexin Peptides: Structure-Activity Relationship Studies.

German NA, Decker AM, Gilmour BP, Thomas BF, Zhang Y. German NA, et al. Among authors: decker am. ACS Med Chem Lett. 2013 Dec 12;4(12):1224-1227. doi: 10.1021/ml400333a. ACS Med Chem Lett. 2013. PMID: 24707347 Free PMC article.

4

Hybrid dopamine uptake blocker-serotonin releaser ligands: a new twist on transporter-focused therapeutics.

Blough BE, Landavazo A, Partilla JS, Baumann MH, Decker AM, Page KM, Rothman RB. Blough BE, et al. Among authors: decker am. ACS Med Chem Lett. 2014 Apr 15;5(6):623-7. doi: 10.1021/ml500113s. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944732 Free PMC article.

5

Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).

German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. German N, et al. Among authors: decker am. J Med Chem. 2014 Sep 25;57(18):7758-69. doi: 10.1021/jm501042u. Epub 2014 Sep 4. J Med Chem. 2014. PMID: 25162172 Free PMC article.

6

Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor.

Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: decker am. ACS Chem Neurosci. 2015 Apr 15;6(4):599-614. doi: 10.1021/cn500330v. Epub 2015 Feb 12. ACS Chem Neurosci. 2015. PMID: 25643283 Free PMC article.

7

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.

Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: decker am. Bioorg Med Chem. 2015 Sep 1;23(17):5709-24. doi: 10.1016/j.bmc.2015.07.013. Epub 2015 Jul 16. Bioorg Med Chem. 2015. PMID: 26216017 Free PMC article.

8

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents.

Carroll FI, Gichinga MG, Kormos CM, Maitra R, Runyon SP, Thomas JB, Mascarella SW, Decker AM, Navarro HA. Carroll FI, et al. Among authors: decker am. Bioorg Med Chem. 2015 Oct 1;23(19):6379-88. doi: 10.1016/j.bmc.2015.08.025. Epub 2015 Aug 25. Bioorg Med Chem. 2015. PMID: 26342544 Free PMC article.

9

Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198).

Chang SD, Brieaddy LE, Harvey JD, Lewin AH, Mascarella SW, Seltzman HH, Reddy PA, Decker AM, McElhinny CJ Jr, Zhong D, Peterson EE, Navarro HA, Bruchas MR, Carroll FI. Chang SD, et al. Among authors: decker am. ACS Chem Neurosci. 2015 Dec 16;6(12):1956-64. doi: 10.1021/acschemneuro.5b00208. Epub 2015 Sep 30. ACS Chem Neurosci. 2015. PMID: 26367173 Free PMC article.

10

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2.

Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpré JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. Thomas JB, et al. Among authors: decker am. ACS Chem Neurosci. 2016 Sep 21;7(9):1225-31. doi: 10.1021/acschemneuro.6b00097. Epub 2016 Jul 13. ACS Chem Neurosci. 2016. PMID: 27359371

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