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Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity.
Doyle SR, Bourguinat C, Nana-Djeunga HC, Kengne-Ouafo JA, Pion SDS, Bopda J, Kamgno J, Wanji S, Che H, Kuesel AC, Walker M, Basáñez MG, Boakye DA, Osei-Atweneboana MY, Boussinesq M, Prichard RK, Grant WN. Doyle SR, et al. PLoS Negl Trop Dis. 2017 Jul 26;11(7):e0005816. doi: 10.1371/journal.pntd.0005816. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28746337 Free PMC article.
Onchocerciasis Control: Vision for the Future from a Ghanian perspective.
Taylor MJ, Awadzi K, Basáñez MG, Biritwum N, Boakye D, Boatin B, Bockarie M, Churcher TS, Debrah A, Edwards G, Hoerauf A, Mand S, Matthews G, Osei-Atweneboana M, Prichard RK, Wanji S, Adjei O. Taylor MJ, et al. Parasit Vectors. 2009 Jan 21;2(1):7. doi: 10.1186/1756-3305-2-7. Parasit Vectors. 2009. PMID: 19154624 Free PMC article.
Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.
Churcher TS, Pion SD, Osei-Atweneboana MY, Prichard RK, Awadzi K, Boussinesq M, Collins RC, Whitworth JA, Basáñez MG. Churcher TS, et al. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16716-21. doi: 10.1073/pnas.0906176106. Epub 2009 Sep 17. Proc Natl Acad Sci U S A. 2009. PMID: 19805362 Free PMC article.
58 results