Musunuru K - Search Results

1

In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.

Chadwick AC, Wang X, Musunuru K. Chadwick AC, et al. Among authors: musunuru k. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1741-1747. doi: 10.1161/ATVBAHA.117.309881. Epub 2017 Jul 27. Arterioscler Thromb Vasc Biol. 2017. PMID: 28751571 Free PMC article.

2

Genome editing of human pluripotent stem cells to generate human cellular disease models.

Musunuru K. Musunuru K. Dis Model Mech. 2013 Jul;6(4):896-904. doi: 10.1242/dmm.012054. Epub 2013 Jun 10. Dis Model Mech. 2013. PMID: 23751357 Free PMC article. Review.

3

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.

Ding Q, Strong A, Patel KM, Ng SL, Gosis BS, Regan SN, Cowan CA, Rader DJ, Musunuru K. Ding Q, et al. Among authors: musunuru k. Circ Res. 2014 Aug 15;115(5):488-92. doi: 10.1161/CIRCRESAHA.115.304351. Epub 2014 Jun 10. Circ Res. 2014. PMID: 24916110 Free PMC article.

4

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

Veres A, Gosis BS, Ding Q, Collins R, Ragavendran A, Brand H, Erdin S, Cowan CA, Talkowski ME, Musunuru K. Veres A, et al. Among authors: musunuru k. Cell Stem Cell. 2014 Jul 3;15(1):27-30. doi: 10.1016/j.stem.2014.04.020. Cell Stem Cell. 2014. PMID: 24996167 Free PMC article.

5

Genome editing of a CArG element in the mouse genome establishes its role in gene expression.

Musunuru K. Musunuru K. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):496-7. doi: 10.1161/ATVBAHA.115.305175. Arterioscler Thromb Vasc Biol. 2015. PMID: 25717176 No abstract available.

6

Genome-Edited Human Pluripotent Stem Cell-Derived Macrophages as a Model of Reverse Cholesterol Transport--Brief Report.

Gupta RM, Meissner TB, Cowan CA, Musunuru K. Gupta RM, et al. Among authors: musunuru k. Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):15-8. doi: 10.1161/ATVBAHA.115.305956. Epub 2015 Nov 5. Arterioscler Thromb Vasc Biol. 2016. PMID: 26543098 Free PMC article.

7

CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo-Brief Report.

Wang X, Raghavan A, Chen T, Qiao L, Zhang Y, Ding Q, Musunuru K. Wang X, et al. Among authors: musunuru k. Arterioscler Thromb Vasc Biol. 2016 May;36(5):783-6. doi: 10.1161/ATVBAHA.116.307227. Epub 2016 Mar 3. Arterioscler Thromb Vasc Biol. 2016. PMID: 26941020 Free PMC article.

8

Genome engineering tools for building cellular models of disease.

Lin J, Musunuru K. Lin J, et al. Among authors: musunuru k. FEBS J. 2016 Sep;283(17):3222-31. doi: 10.1111/febs.13763. Epub 2016 Jun 22. FEBS J. 2016. PMID: 27218233 Free PMC article. Review.

9

Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing.

Lin J, Hu Y, Nunez S, Foulkes AS, Cieply B, Xue C, Gerelus M, Li W, Zhang H, Rader DJ, Musunuru K, Li M, Reilly MP. Lin J, et al. Among authors: musunuru k. Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1434-47. doi: 10.1161/ATVBAHA.116.307573. Epub 2016 May 26. Arterioscler Thromb Vasc Biol. 2016. PMID: 27230130 Free PMC article.

10

Genome editing in cardiovascular diseases.

Strong A, Musunuru K. Strong A, et al. Among authors: musunuru k. Nat Rev Cardiol. 2017 Jan;14(1):11-20. doi: 10.1038/nrcardio.2016.139. Epub 2016 Sep 9. Nat Rev Cardiol. 2017. PMID: 27609628 Review.

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