Günther S - Search Results

1

Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles.

Hügle M, Lucas X, Ostrovskyi D, Regenass P, Gerhardt S, Einsle O, Hau M, Jung M, Breit B, Günther S, Wohlwend D. Hügle M, et al. Among authors: gunther s. Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12476-12480. doi: 10.1002/anie.201705516. Epub 2017 Sep 7. Angew Chem Int Ed Engl. 2017. PMID: 28766825

2

Tetrahydroxynaphthalene reductase: catalytic properties of an enzyme involved in reductive asymmetric naphthol dearomatization.

Schätzle MA, Flemming S, Husain SM, Richter M, Günther S, Müller M. Schätzle MA, et al. Among authors: gunther s. Angew Chem Int Ed Engl. 2012 Mar 12;51(11):2643-6. doi: 10.1002/anie.201107695. Epub 2012 Feb 3. Angew Chem Int Ed Engl. 2012. PMID: 22308069

3

Regio- and stereoselective oxidative phenol coupling in Aspergillus niger.

Gil Girol C, Fisch KM, Heinekamp T, Günther S, Hüttel W, Piel J, Brakhage AA, Müller M. Gil Girol C, et al. Among authors: gunther s. Angew Chem Int Ed Engl. 2012 Sep 24;51(39):9788-91. doi: 10.1002/anie.201203603. Epub 2012 Sep 3. Angew Chem Int Ed Engl. 2012. PMID: 22945023

4

StreptomeDB: a resource for natural compounds isolated from Streptomyces species.

Lucas X, Senger C, Erxleben A, Grüning BA, Döring K, Mosch J, Flemming S, Günther S. Lucas X, et al. Among authors: gunther s. Nucleic Acids Res. 2013 Jan;41(Database issue):D1130-6. doi: 10.1093/nar/gks1253. Epub 2012 Nov 28. Nucleic Acids Res. 2013. PMID: 23193280 Free PMC article.

5

Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies.

Lucas X, Simon S, Schubert R, Günther S. Lucas X, et al. Among authors: gunther s. PLoS One. 2013 Apr 9;8(4):e60679. doi: 10.1371/journal.pone.0060679. Print 2013. PLoS One. 2013. PMID: 23593281 Free PMC article.

6

4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.

Lucas X, Wohlwend D, Hügle M, Schmidtkunz K, Gerhardt S, Schüle R, Jung M, Einsle O, Günther S. Lucas X, et al. Among authors: gunther s. Angew Chem Int Ed Engl. 2013 Dec 23;52(52):14055-9. doi: 10.1002/anie.201307652. Epub 2013 Nov 24. Angew Chem Int Ed Engl. 2013. PMID: 24272870 No abstract available.

7

Targeting the BET family for the treatment of leukemia.

Lucas X, Günther S. Lucas X, et al. Among authors: gunther s. Epigenomics. 2014 Apr;6(2):153-5. doi: 10.2217/epi.14.5. Epigenomics. 2014. PMID: 24811781 No abstract available.

8

Metabolic pathway monitoring of phenalinolactone biosynthesis from Streptomyces sp. Tü6071 by liquid chromatography/mass spectrometry coupling.

Kiske C, Erxleben A, Lucas X, Willmann L, Klementz D, Günther S, Römer W, Kammerer B. Kiske C, et al. Among authors: gunther s. Rapid Commun Mass Spectrom. 2014 Jul 15;28(13):1459-67. doi: 10.1002/rcm.6920. Rapid Commun Mass Spectrom. 2014. PMID: 24861595

9

Using chiral molecules as an approach to address low-druggability recognition sites.

Lucas X, Günther S. Lucas X, et al. Among authors: gunther s. J Comput Chem. 2014 Nov 5;35(29):2114-21. doi: 10.1002/jcc.23726. Epub 2014 Sep 16. J Comput Chem. 2014. PMID: 25223950

10

The purchasable chemical space: a detailed picture.

Lucas X, Grüning BA, Bleher S, Günther S. Lucas X, et al. Among authors: gunther s. J Chem Inf Model. 2015 May 26;55(5):915-24. doi: 10.1021/acs.jcim.5b00116. Epub 2015 Apr 30. J Chem Inf Model. 2015. PMID: 25894297

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