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B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.
Milillo MA, Velásquez LN, Trotta A, Delpino MV, Marinho FV, Balboa L, Vermeulen M, Espindola SL, Rodriguez-Rodrigues N, Fernández GC, Oliveira SC, Giambartolomei GH, Barrionuevo P. Milillo MA, et al. Among authors: oliveira sc. PLoS Pathog. 2017 Aug 2;13(8):e1006527. doi: 10.1371/journal.ppat.1006527. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28767704 Free PMC article.
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
Pasquevich KA, García Samartino C, Coria LM, Estein SM, Zwerdling A, Ibañez AE, Barrionuevo P, Oliveira FS, Carvalho NB, Borkowski J, Oliveira SC, Warzecha H, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: oliveira sc, oliveira fs. J Immunol. 2010 May 1;184(9):5200-12. doi: 10.4049/jimmunol.0902209. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351187
An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
Pasquevich KA, Ibañez AE, Coria LM, García Samartino C, Estein SM, Zwerdling A, Barrionuevo P, Oliveira FS, Seither C, Warzecha H, Oliveira SC, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: oliveira sc, oliveira fs. PLoS One. 2011 Jan 14;6(1):e16203. doi: 10.1371/journal.pone.0016203. PLoS One. 2011. PMID: 21264260 Free PMC article.
451 results