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The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia.
McElligott AM, Maginn EN, Greene LM, McGuckin S, Hayat A, Browne PV, Butini S, Campiani G, Catherwood MA, Vandenberghe E, Williams DC, Zisterer DM, Lawler M. McElligott AM, et al. Among authors: browne pv. Cancer Res. 2009 Nov 1;69(21):8366-75. doi: 10.1158/0008-5472.CAN-09-0131. Epub 2009 Oct 13. Cancer Res. 2009. PMID: 19826055 Free article.
BRAF V600E-Negative Hairy Cell Leukaemia.
Langabeer SE, O'Brien D, McElligott AM, Lavin M, Browne PV. Langabeer SE, et al. Among authors: browne pv. Case Rep Hematol. 2013;2013:513049. doi: 10.1155/2013/513049. Epub 2013 Apr 9. Case Rep Hematol. 2013. PMID: 23653869 Free PMC article.
A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
Amet R, Previtali V, Mihigo HB, Sheridan E, Brophy S, Hante NK, Santos-Martinez MJ, Hayden PJ, Browne PV, Rozas I, McElligott AM, Zisterer DM. Amet R, et al. Among authors: browne pv. Life Sci. 2022 Feb 1;290:120236. doi: 10.1016/j.lfs.2021.120236. Epub 2021 Dec 22. Life Sci. 2022. PMID: 34953891
PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells.
Maginn EN, Browne PV, Hayden P, Vandenberghe E, MacDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM. Maginn EN, et al. Among authors: browne pv. Br J Cancer. 2011 Jan 18;104(2):281-9. doi: 10.1038/sj.bjc.6606035. Epub 2010 Dec 21. Br J Cancer. 2011. PMID: 21179037 Free PMC article.
84 results