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Natural killer cell-mediated inflammation resolution is disabled in severe asthma.
Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Duvall MG, et al. Among authors: cernadas m. Sci Immunol. 2017 Mar 10;2(9):eaam5446. doi: 10.1126/sciimmunol.aam5446. Sci Immunol. 2017. PMID: 28783702 Free PMC article.
Adam8 limits the development of allergic airway inflammation in mice.
Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA. Knolle MD, et al. Among authors: cernadas m. J Immunol. 2013 Jun 15;190(12):6434-49. doi: 10.4049/jimmunol.1202329. Epub 2013 May 13. J Immunol. 2013. PMID: 23670189 Free PMC article.
Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function.
Reid B, Girodet PO, Boomer JS, Abdel-Gadir A, Zheng K, Wechsler ME, Bacharier LB, Kunselman SJ, King TS, Israel E, Castro M, Cernadas M, Green JM. Reid B, et al. Among authors: cernadas m. J Allergy Clin Immunol. 2016 Jul;138(1):286-289.e9. doi: 10.1016/j.jaci.2015.11.030. Epub 2016 Feb 10. J Allergy Clin Immunol. 2016. PMID: 26874367 Free PMC article. Clinical Trial. No abstract available.
Alternative Macrophage Activation Is Increased in Asthma.
Girodet PO, Nguyen D, Mancini JD, Hundal M, Zhou X, Israel E, Cernadas M. Girodet PO, et al. Among authors: cernadas m. Am J Respir Cell Mol Biol. 2016 Oct;55(4):467-475. doi: 10.1165/rcmb.2015-0295OC. Am J Respir Cell Mol Biol. 2016. PMID: 27248771 Free PMC article.
ALX receptor ligands define a biochemical endotype for severe asthma.
Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. Ricklefs I, et al. Among authors: cernadas m. JCI Insight. 2017 Jul 20;2(14):e93534. doi: 10.1172/jci.insight.93534. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724795 Free PMC article.
ALX receptor ligands define a biochemical endotype for severe asthma.
Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators. Ricklefs I, et al. Among authors: cernadas m. JCI Insight. 2018 Mar 22;3(6):e120932. doi: 10.1172/jci.insight.120932. JCI Insight. 2018. PMID: 29563345 Free PMC article. No abstract available.
Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.
Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators. Krishnamoorthy N, et al. Among authors: cernadas m. Sci Immunol. 2018 Aug 3;3(26):eaao4747. doi: 10.1126/sciimmunol.aao4747. Sci Immunol. 2018. PMID: 30076281 Free PMC article.
67 results