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Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.
Narvaez AJ, Ber S, Crooks A, Emery A, Hardwick B, Guarino Almeida E, Huggins DJ, Perera D, Roberts-Thomson M, Azzarelli R, Hood FE, Prior IA, Walker DW, Boyce R, Boyle RG, Barker SP, Torrance CJ, McKenzie GJ, Venkitaraman AR. Narvaez AJ, et al. Among authors: prior ia. Cell Chem Biol. 2017 Aug 17;24(8):1017-1028.e7. doi: 10.1016/j.chembiol.2017.07.009. Epub 2017 Aug 10. Cell Chem Biol. 2017. PMID: 28807782 Free PMC article.
Decoding RAS isoform and codon-specific signalling.
Newlaczyl AU, Hood FE, Coulson JM, Prior IA. Newlaczyl AU, et al. Among authors: prior ia. Biochem Soc Trans. 2014 Aug;42(4):742-6. doi: 10.1042/BST20140057. Biochem Soc Trans. 2014. PMID: 25109951 Free PMC article. Review.
Isoform-specific Ras signaling is growth factor dependent.
Hood FE, Klinger B, Newlaczyl AU, Sieber A, Dorel M, Oliver SP, Coulson JM, Blüthgen N, Prior IA. Hood FE, et al. Among authors: prior ia. Mol Biol Cell. 2019 Apr 15;30(9):1108-1117. doi: 10.1091/mbc.E18-10-0676. Epub 2019 Feb 20. Mol Biol Cell. 2019. PMID: 30785867 Free PMC article.
The Frequency of Ras Mutations in Cancer.
Prior IA, Hood FE, Hartley JL. Prior IA, et al. Cancer Res. 2020 Jul 15;80(14):2969-2974. doi: 10.1158/0008-5472.CAN-19-3682. Epub 2020 Mar 24. Cancer Res. 2020. PMID: 32209560 Free PMC article. Review.
Absolute Quantitation of GTPase Protein Abundance.
Hood FE, Sahraoui YM, Jenkins RE, Prior I. Hood FE, et al. Methods Mol Biol. 2021;2262:65-90. doi: 10.1007/978-1-0716-1190-6_4. Methods Mol Biol. 2021. PMID: 33977471
202 results