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Page 1
A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.
Sierro F, Evrard M, Rizzetto S, Melino M, Mitchell AJ, Florido M, Beattie L, Walters SB, Tay SS, Lu B, Holz LE, Roediger B, Wong YC, Warren A, Ritchie W, McGuffog C, Weninger W, Le Couteur DG, Ginhoux F, Britton WJ, Heath WR, Saunders BM, McCaughan GW, Luciani F, MacDonald KPA, Ng LG, Bowen DG, Bertolino P. Sierro F, et al. Among authors: mcguffog c. Immunity. 2017 Aug 15;47(2):374-388.e6. doi: 10.1016/j.immuni.2017.07.018. Immunity. 2017. PMID: 28813662 Free article.
Hepatocyte entry leads to degradation of autoreactive CD8 T cells.
Benseler V, Warren A, Vo M, Holz LE, Tay SS, Le Couteur DG, Breen E, Allison AC, van Rooijen N, McGuffog C, Schlitt HJ, Bowen DG, McCaughan GW, Bertolino P. Benseler V, et al. Among authors: mcguffog c. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16735-40. doi: 10.1073/pnas.1112251108. Epub 2011 Sep 20. Proc Natl Acad Sci U S A. 2011. PMID: 21933957 Free PMC article.
Gene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts.
Cunningham EC, Tay SS, Wang C, Rtshiladze M, Wang ZZ, McGuffog C, Cubitt J, McCaughan GW, Alexander IE, Bertolino P, Sharland AF, Bowen DG, Bishop GA. Cunningham EC, et al. Among authors: mcguffog c. Transplantation. 2013 Jan 15;95(1):70-7. doi: 10.1097/TP.0b013e318278d39a. Transplantation. 2013. PMID: 23263501
Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses.
Tay SS, Wong YC, McDonald DM, Wood NA, Roediger B, Sierro F, Mcguffog C, Alexander IE, Bishop GA, Gamble JR, Weninger W, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. Among authors: mcguffog c. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2540-9. doi: 10.1073/pnas.1406674111. Epub 2014 Jun 10. Proc Natl Acad Sci U S A. 2014. PMID: 24927525 Free PMC article.
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
Tay SS, Wong YC, Roediger B, Sierro F, Lu B, McDonald DM, McGuffog CM, Meyer NJ, Alexander IE, Parish IA, Heath WR, Weninger W, Bishop GA, Gamble JR, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. Among authors: mcguffog cm. J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28. J Immunol. 2014. PMID: 25070847
Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.
Paul-Heng M, Leong M, Cunningham E, Bunker DLJ, Bremner K, Wang Z, Wang C, Tay SS, McGuffog C, Logan GJ, Alexander IE, Hu M, Alexander SI, Sparwasser TD, Bertolino P, Bowen DG, Bishop GA, Sharland A. Paul-Heng M, et al. Among authors: mcguffog c. JCI Insight. 2018 Aug 9;3(15):e97500. doi: 10.1172/jci.insight.97500. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089715 Free PMC article.
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