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Adenoviral Type 35 and 26 Vectors with a Bidirectional Expression Cassette in the E1 Region Show an Improved Genetic Stability Profile and Potent Transgene-Specific Immune Response.
Vujadinovic M, Wunderlich K, Callendret B, Koning M, Vermeulen M, Sanders B, van der Helm E, Gecgel A, Spek D, de Boer K, Stalknecht M, Serroyen J, Grazia Pau M, Schuitemaker H, Zahn R, Custers J, Vellinga J. Vujadinovic M, et al. Among authors: van der helm e. Hum Gene Ther. 2018 Mar;29(3):337-351. doi: 10.1089/hum.2017.023. Epub 2017 Nov 30. Hum Gene Ther. 2018. PMID: 28816084 Free PMC article.
Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species.
Zahn R, Gillisen G, Roos A, Koning M, van der Helm E, Spek D, Weijtens M, Grazia Pau M, Radošević K, Weverling GJ, Custers J, Vellinga J, Schuitemaker H, Goudsmit J, Rodríguez A. Zahn R, et al. Among authors: van der helm e. PLoS One. 2012;7(12):e44115. doi: 10.1371/journal.pone.0044115. Epub 2012 Dec 6. PLoS One. 2012. PMID: 23236343 Free PMC article.
Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.
Holterman L, Vogels R, van der Vlugt R, Sieuwerts M, Grimbergen J, Kaspers J, Geelen E, van der Helm E, Lemckert A, Gillissen G, Verhaagh S, Custers J, Zuijdgeest D, Berkhout B, Bakker M, Quax P, Goudsmit J, Havenga M. Holterman L, et al. Among authors: van der vlugt r, van der helm e. J Virol. 2004 Dec;78(23):13207-15. doi: 10.1128/JVI.78.23.13207-13215.2004. J Virol. 2004. PMID: 15542673 Free PMC article.
High-level expression of recombinant IgG in the human cell line per.c6.
Jones D, Kroos N, Anema R, van Montfort B, Vooys A, van der Kraats S, van der Helm E, Smits S, Schouten J, Brouwer K, Lagerwerf F, van Berkel P, Opstelten DJ, Logtenberg T, Bout A. Jones D, et al. Among authors: van der kraats s, van montfort b, van berkel p, van der helm e. Biotechnol Prog. 2003 Jan-Feb;19(1):163-8. doi: 10.1021/bp025574h. Biotechnol Prog. 2003. PMID: 12573020
Engineered phage with antibacterial CRISPR-Cas selectively reduce E. coli burden in mice.
Gencay YE, Jasinskytė D, Robert C, Semsey S, Martínez V, Petersen AØ, Brunner K, de Santiago Torio A, Salazar A, Turcu IC, Eriksen MK, Koval L, Takos A, Pascal R, Schou TS, Bayer L, Bryde T, Johansen KC, Bak EG, Smrekar F, Doyle TB, Satlin MJ, Gram A, Carvalho J, Jessen L, Hallström B, Hink J, Damholt B, Troy A, Grove M, Clube J, Grøndahl C, Haaber JK, van der Helm E, Zdravkovic M, Sommer MOA. Gencay YE, et al. Among authors: van der helm e. Nat Biotechnol. 2024 Feb;42(2):265-274. doi: 10.1038/s41587-023-01759-y. Epub 2023 May 4. Nat Biotechnol. 2024. PMID: 37142704 Free PMC article.
Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Edavettal S, Cejudo-Martin P, Dasgupta B, Yang D, Buschman MD, Domingo D, Van Kolen K, Jaiprasat P, Gordon R, Schutsky K, Geist B, Taylor N, Soubrane CH, Van Der Helm E, LaCombe A, Ainekulu Z, Lacy E, Aligo J, Ho J, He Y, Lebowitz PF, Patterson JT, Scheer JM, Singh S. Edavettal S, et al. Among authors: van der helm e. Med. 2022 Dec 9;3(12):860-882.e15. doi: 10.1016/j.medj.2022.09.007. Epub 2022 Oct 17. Med. 2022. PMID: 36257298 Free article.
A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics.
Malla S, van der Helm E, Darbani B, Wieschalka S, Förster J, Borodina I, Sommer MOA. Malla S, et al. Among authors: van der helm e. Front Microbiol. 2022 Apr 14;13:855736. doi: 10.3389/fmicb.2022.855736. eCollection 2022. Front Microbiol. 2022. PMID: 35495724 Free PMC article.
30 results