Xu A - Search Results

1

Li-Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53.

Zhou R, Xu A, Gingold J, Strong LC, Zhao R, Lee DF. Zhou R, et al. Among authors: xu a. Trends Pharmacol Sci. 2017 Oct;38(10):908-927. doi: 10.1016/j.tips.2017.07.004. Epub 2017 Aug 14. Trends Pharmacol Sci. 2017. PMID: 28818333 Free PMC article. Review.

2

Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase.

Tu J, Huo Z, Liu M, Wang D, Xu A, Zhou R, Zhu D, Gingold J, Shen J, Zhao R, Lee DF. Tu J, et al. Among authors: xu a. Stem Cell Res. 2018 Apr;28:29-32. doi: 10.1016/j.scr.2018.01.021. Epub 2018 Feb 28. Stem Cell Res. 2018. PMID: 29414415 Free PMC article.

3

A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing.

Zhou R, Xu A, Wang D, Zhu D, Mata H, Huo Z, Tu J, Liu M, Mohamed AMT, Jewell BE, Gingold J, Xia W, Rao PH, Hung MC, Zhao R, Lee DF. Zhou R, et al. Among authors: xu a. Stem Cell Res. 2018 Mar;27:131-135. doi: 10.1016/j.scr.2018.01.035. Epub 2018 Jan 28. Stem Cell Res. 2018. PMID: 29414603 Free article.

4

Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.

Xu A, Zhou R, Tu J, Huo Z, Zhu D, Wang D, Gingold JA, Mata H, Rao PH, Liu M, Mohamed AMT, Kong CSL, Jewell BE, Xia W, Zhao R, Hung MC, Lee DF. Xu A, et al. Stem Cell Res. 2018 May;29:215-219. doi: 10.1016/j.scr.2018.04.013. Epub 2018 Apr 27. Stem Cell Res. 2018. PMID: 29730572 Free PMC article.

5

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells.

Zhou R, Xu A, Tu J, Liu M, Gingold JA, Zhao R, Lee DF. Zhou R, et al. Among authors: xu a. J Vis Exp. 2018 Jun 13;(136):57664. doi: 10.3791/57664. J Vis Exp. 2018. PMID: 29985349 Free PMC article.

6

Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation.

Jewell BE, Liu M, Lu L, Zhou R, Tu J, Zhu D, Huo Z, Xu A, Wang D, Mata H, Jin W, Xia W, Rao PH, Zhao R, Hung MC, Wang LL, Lee DF. Jewell BE, et al. Among authors: xu a. Stem Cell Res. 2018 Dec;33:36-40. doi: 10.1016/j.scr.2018.10.003. Epub 2018 Oct 2. Stem Cell Res. 2018. PMID: 30312871 Free PMC article.

7

Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism.

Kim H, Yoo S, Zhou R, Xu A, Bernitz JM, Yuan Y, Gomes AM, Daniel MG, Su J, Demicco EG, Zhu J, Moore KA, Lee DF, Lemischka IR, Schaniel C. Kim H, et al. Among authors: xu a. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11128-E11137. doi: 10.1073/pnas.1814044115. Epub 2018 Nov 1. Proc Natl Acad Sci U S A. 2018. PMID: 30385632 Free PMC article.

8

Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing.

Huo Z, Tu J, Xu A, Li Y, Wang D, Liu M, Zhou R, Zhu D, Lin Y, Gingold JA, Yen CJ, Xiao H, Zhao R. Huo Z, et al. Among authors: xu a. Stem Cell Res. 2019 Jan;34:101360. doi: 10.1016/j.scr.2018.101360. Epub 2018 Nov 30. Stem Cell Res. 2019. PMID: 30640060 Free article.

9

LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes.

Xu A, Huang MF, Zhu D, Gingold JA, Bazer DA, Chang B, Wang D, Lai CC, Lemischka IR, Zhao R, Lee DF. Xu A, et al. Front Genet. 2021 Jan 15;11:611823. doi: 10.3389/fgene.2020.611823. eCollection 2020. Front Genet. 2021. PMID: 33519915 Free PMC article.

10

Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1.

Huang PS, Wen MH, Xie X, Xu A, Lee DF, Chen TY. Huang PS, et al. Among authors: xu a. Stem Cell Res. 2021 Jul;54:102415. doi: 10.1016/j.scr.2021.102415. Epub 2021 Jun 6. Stem Cell Res. 2021. PMID: 34118566 Free PMC article.

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