Seeger MA - Search Results

1

Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin.

Kramer L, Renko M, Završnik J, Turk D, Seeger MA, Vasiljeva O, Grütter MG, Turk V, Turk B. Kramer L, et al. Among authors: seeger ma. Theranostics. 2017 Jul 8;7(11):2806-2821. doi: 10.7150/thno.19081. eCollection 2017. Theranostics. 2017. PMID: 28824717 Free PMC article.

2

Designed ankyrin repeat protein binders for the crystallization of AcrB: plasticity of the dominant interface.

Monroe N, Sennhauser G, Seeger MA, Briand C, Grütter MG. Monroe N, et al. Among authors: seeger ma. J Struct Biol. 2011 May;174(2):269-81. doi: 10.1016/j.jsb.2011.01.014. Epub 2011 Feb 4. J Struct Biol. 2011. PMID: 21296164

3

Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation.

Hohl M, Briand C, Grütter MG, Seeger MA. Hohl M, et al. Among authors: seeger ma. Nat Struct Mol Biol. 2012 Mar 25;19(4):395-402. doi: 10.1038/nsmb.2267. Nat Struct Mol Biol. 2012. PMID: 22447242

4

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.

Eicher T, Cha HJ, Seeger MA, Brandstätter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grütter MG, Diederichs K, Pos KM. Eicher T, et al. Among authors: seeger ma. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5687-92. doi: 10.1073/pnas.1114944109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451937 Free PMC article.

5

Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin.

Mittal A, Böhm S, Grütter MG, Bordignon E, Seeger MA. Mittal A, et al. Among authors: seeger ma. J Biol Chem. 2012 Jun 8;287(24):20395-406. doi: 10.1074/jbc.M112.359794. Epub 2012 Apr 20. J Biol Chem. 2012. PMID: 22523072 Free PMC article.

6

Tuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin binders.

Seeger MA, Mittal A, Velamakanni S, Hohl M, Schauer S, Salaa I, Grütter MG, van Veen HW. Seeger MA, et al. PLoS One. 2012;7(6):e37845. doi: 10.1371/journal.pone.0037845. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675494 Free PMC article.

7

Design, construction, and characterization of a second-generation DARP in library with reduced hydrophobicity.

Seeger MA, Zbinden R, Flütsch A, Gutte PG, Engeler S, Roschitzki-Voser H, Grütter MG. Seeger MA, et al. Protein Sci. 2013 Sep;22(9):1239-57. doi: 10.1002/pro.2312. Epub 2013 Aug 6. Protein Sci. 2013. PMID: 23868333 Free PMC article.

8

Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.

Hohl M, Hürlimann LM, Böhm S, Schöppe J, Grütter MG, Bordignon E, Seeger MA. Hohl M, et al. Among authors: seeger ma. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11025-30. doi: 10.1073/pnas.1400485111. Epub 2014 Jul 16. Proc Natl Acad Sci U S A. 2014. PMID: 25030449 Free PMC article.

9

A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.

Bukowska MA, Hohl M, Geertsma ER, Hürlimann LM, Grütter MG, Seeger MA. Bukowska MA, et al. Among authors: seeger ma. Biochemistry. 2015 May 19;54(19):3086-99. doi: 10.1021/acs.biochem.5b00188. Epub 2015 May 7. Biochemistry. 2015. PMID: 25947941

10

X-Ray Structure of a Heterodimeric ABC Transporter Crystallized in its Inward-Facing Conformation.

Hohl M, Grütter MG, Seeger MA. Hohl M, et al. Among authors: seeger ma. Chimia (Aarau). 2012 Oct 31;66(10):802. doi: 10.2533/chimia.2012.802. Chimia (Aarau). 2012. PMID: 28978392 Free article. No abstract available.

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