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Page 1
Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine.
Walter NM, Wentsch HK, Bührmann M, Bauer SM, Döring E, Mayer-Wrangowski S, Sievers-Engler A, Willemsen-Seegers N, Zaman G, Buijsman R, Lämmerhofer M, Rauh D, Laufer SA. Walter NM, et al. Among authors: lammerhofer m. J Med Chem. 2017 Oct 12;60(19):8027-8054. doi: 10.1021/acs.jmedchem.7b00745. Epub 2017 Sep 7. J Med Chem. 2017. PMID: 28834431
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Hanke T, Dehm F, Liening S, Popella SD, Maczewsky J, Pillong M, Kunze J, Weinigel C, Barz D, Kaiser A, Wurglics M, Lämmerhofer M, Schneider G, Sautebin L, Schubert-Zsilavecz M, Werz O. Hanke T, et al. Among authors: lammerhofer m. J Med Chem. 2013 Nov 27;56(22):9031-44. doi: 10.1021/jm401557w. Epub 2013 Nov 15. J Med Chem. 2013. PMID: 24171493
Mastering analytical challenges for the characterization of pentacyclic triterpene mono- and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC and hyphenation with APCI-QTOF-MS.
Nicolaus C, Sievers-Engler A, Murillo R, D'Ambrosio M, Lämmerhofer M, Merfort I. Nicolaus C, et al. Among authors: lammerhofer m. J Pharm Biomed Anal. 2016 Jan 25;118:195-205. doi: 10.1016/j.jpba.2015.10.025. Epub 2015 Oct 21. J Pharm Biomed Anal. 2016. PMID: 26562182
Surface-crosslinked poly(3-mercaptopropyl)methylsiloxane-coatings on silica as new platform for low-bleed mass spectrometry-compatible functionalized stationary phases synthesized via thiol-ene click reaction.
Zimmermann A, Horak J, Sievers-Engler A, Sanwald C, Lindner W, Kramer M, Lämmerhofer M. Zimmermann A, et al. Among authors: lammerhofer m. J Chromatogr A. 2016 Mar 4;1436:73-83. doi: 10.1016/j.chroma.2016.01.058. Epub 2016 Feb 2. J Chromatogr A. 2016. PMID: 26860050
267 results