Christianson DW - Search Results

1

Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.

Porter NJ, Christianson DW. Porter NJ, et al. Among authors: christianson dw. ACS Chem Biol. 2017 Sep 15;12(9):2281-2286. doi: 10.1021/acschembio.7b00330. Epub 2017 Aug 30. ACS Chem Biol. 2017. PMID: 28846375 Free PMC article.

2

Design of amino acid sulfonamides as transition-state analogue inhibitors of arginase.

Cama E, Shin H, Christianson DW. Cama E, et al. Among authors: christianson dw. J Am Chem Soc. 2003 Oct 29;125(43):13052-7. doi: 10.1021/ja036365b. J Am Chem Soc. 2003. PMID: 14570477

3

Design of amino acid aldehydes as transition-state analogue inhibitors of arginase.

Shin H, Cama E, Christianson DW. Shin H, et al. Among authors: christianson dw. J Am Chem Soc. 2004 Aug 25;126(33):10278-84. doi: 10.1021/ja047788w. J Am Chem Soc. 2004. PMID: 15315440

4

Arginase: structure, mechanism, and physiological role in male and female sexual arousal.

Christianson DW. Christianson DW. Acc Chem Res. 2005 Mar;38(3):191-201. doi: 10.1021/ar040183k. Acc Chem Res. 2005. PMID: 15766238 Review.

5

Mechanistic inferences from the binding of ligands to LpxC, a metal-dependent deacetylase.

Gennadios HA, Whittington DA, Li X, Fierke CA, Christianson DW. Gennadios HA, et al. Among authors: christianson dw. Biochemistry. 2006 Jul 4;45(26):7940-8. doi: 10.1021/bi060823m. Biochemistry. 2006. PMID: 16800620 Free PMC article.

6

Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.

Di Costanzo L, Pique ME, Christianson DW. Di Costanzo L, et al. Among authors: christianson dw. J Am Chem Soc. 2007 May 23;129(20):6388-9. doi: 10.1021/ja071567j. Epub 2007 May 1. J Am Chem Soc. 2007. PMID: 17469833 Free PMC article.

7

(S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster.

Zakharian TY, Di Costanzo L, Christianson DW. Zakharian TY, et al. Among authors: christianson dw. J Am Chem Soc. 2008 Dec 24;130(51):17254-5. doi: 10.1021/ja807702q. J Am Chem Soc. 2008. PMID: 19032027

8

Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.

Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW. Dowling DP, et al. Among authors: christianson dw. Biochemistry. 2008 Dec 23;47(51):13554-63. doi: 10.1021/bi801610c. Biochemistry. 2008. PMID: 19053282 Free PMC article.

9

Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function.

Dowling DP, Gattis SG, Fierke CA, Christianson DW. Dowling DP, et al. Among authors: christianson dw. Biochemistry. 2010 Jun 22;49(24):5048-56. doi: 10.1021/bi1005046. Biochemistry. 2010. PMID: 20545365 Free PMC article.

10

Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases.

Lombardi PM, Angell HD, Whittington DA, Flynn EF, Rajashankar KR, Christianson DW. Lombardi PM, et al. Among authors: christianson dw. Biochemistry. 2011 Mar 22;50(11):1808-17. doi: 10.1021/bi101859k. Epub 2011 Jan 26. Biochemistry. 2011. PMID: 21268586 Free PMC article.

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